Browse Category

Genetics News 21 August 2025 - 23 September 2025

Biting Back: How CRISPR-Edited Mice Could Stop the Lyme Disease Plague

Biting Back: How CRISPR-Edited Mice Could Stop the Lyme Disease Plague

Lyme Disease on the Rise – And Why Mice Matter Lyme disease is often called a “plague” on Nantucket. The tiny Massachusetts island, famed for its beaches, has one of the nation’s highest infection rates media.mit.edu. About 15% of Nantucket’s residents have contracted Lyme disease, which causes fevers, rashes, swollen joints, and even nerve damage cbsnews.com cbsnews.com. The culprit is a spiral-shaped bacteria (Borrelia burgdorferi) spread by black-legged ticks, commonly known as deer ticks. But while deer and ticks get most of the blame, scientists point to a different host at the heart of Lyme’s spread: the white-footed mouse cbsnews.com.
23 September 2025
CRISPR ‘Prime Editing’ Breakthrough Cures Genetic Liver Disease in Mice

CRISPR ‘Prime Editing’ Breakthrough Cures Genetic Liver Disease in Mice

Breaking the Genetic “Spell” of a Liver Disease Phenylketonuria (PKU) is a hereditary metabolic liver disorder where a single DNA typo disrupts the PAH enzyme that breaks down phenylalanine, an amino acid nature.com fiercebiotech.com. Without a working PAH enzyme, phenylalanine builds up to toxic levels, causing brain damage, intellectual disability, and seizures if untreated. Newborn screening identifies PKU early, and patients are put on a strict lifetime diet limiting protein (to keep blood Phe 120–360 µM) pennmedicine.org fiercebiotech.com. Even with dietary control and medications, many patients struggle – foods high in protein are largely off-limits, and even newer drugs like
15 September 2025
Neanderthal-Human Hybrid Shocks Scientists; AI Breakthroughs & More – Science Roundup (Aug 25–26, 2025)

Neanderthal-Human Hybrid Shocks Scientists; AI Breakthroughs & More – Science Roundup (Aug 25–26, 2025)

Cell Metabolism reports that gut bacteria–produced D-lactate leaks into the bloodstream to drive hepatic overproduction of glucose and fat, and a safe polymer trap in the gut bound D-lactate to improve blood sugar, insulin resistance, and fatty liver in obese mice (senior author Professor Jonathan Schertzer). Baylor College of Medicine researchers show metformin’s brain action: suppression of Rap1 in the hypothalamus is required for glucose lowering, with Rap1-lacking mice unresponsive to low-dose metformin and brain infusion lowering blood sugar in diabetics (Science Advances; lead author Dr. Makoto Fukuda). A global study of over 100,000 youths links first smartphone ownership by
From a Gene-Edited Baby to Uranus’ Hidden Moon: August 2025’s Biggest Science Breakthroughs

From a Gene-Edited Baby to Uranus’ Hidden Moon: August 2025’s Biggest Science Breakthroughs

August 2025 was packed with scientific advances across health, space, physics, AI, environment, energy, biology, chemistry, and technology. Below we round up the most significant global science news of the month, with each section highlighting key developments and expert insights. Health & Medicine Space & Astronomy Physics Artificial Intelligence (AI is also accelerating drug discovery: in August, one team used AI to scan genomes of Archaea and identified new antimicrobial molecules effective against superbugs sci.news sci.news. This approach could vastly expand our library of antibiotic candidates, demonstrating AI’s growing role in biology and medicine.) Climate Science Environment & Ecology (In
21 August 2025
Go toTop