- Stock Price (Nov 5, 2025): Recursion Pharmaceuticals (NASDAQ: RXRX) is trading around $5 per share, after a recent slide of ~15% over the past week [1]. Shares are down roughly 27% year-to-date and sit ~55% below their 52-week high (~$11) amid biotech sector volatility [2]. Market sentiment is cautious but not bearish – the analyst consensus is “Hold” with a median 12-month price target about 23% above the current price [3].
- Recent News (Early Nov 2025): Recursion announced third-quarter 2025 results on Nov 5, highlighted by a large earnings miss but a major partnership win. Q3 revenue came in at just $5.0 million (vs ~$17 million expected), and net loss widened to $162.3 million, underscoring hefty R&D spending [4]. However, the company earned a $30 million milestone payment from Roche/Genentech for a breakthrough “microglial map” in neuroscience [5]. On the same day, Recursion also announced a CEO transition – Co-Founder Chris Gibson will step aside to become Chairman, with Najat Khan, Ph.D. (currently Chief R&D and Commercial Officer) taking over as CEO effective Jan 1, 2026 [6]. This leadership change aims to drive the next phase of growth, though the stock initially dipped on the news.
- Market Sentiment: Despite cutting ~20% of its workforce in mid-2025 to rein in costs [7] [8], Recursion maintains a strong cash position (~$785 million as of Oct 2025) sufficient to fund operations through 2027 without additional financing [9]. Investors remain intrigued by Recursion’s AI-driven drug discovery platform and big-pharma partnerships, but the lack of any approved drugs or late-stage trial successes keeps risk high [10]. In short, Recursion is viewed as a high-risk, high-potential TechBio stock – its innovative approach and multi-billion-dollar partner deals “keep hopes alive” even as ongoing losses and long development timelines temper near-term excitement [11] [12].
Below we dive into a detailed analysis of RXRX – covering the latest developments, the company’s AI-powered business model, financials, key partnerships, expert commentary, technical trends, forecasts, and how Recursion compares to other AI-focused biotech players.
Latest Developments and News (Early November 2025)
Q3 2025 Earnings & Milestone: Recursion’s third-quarter 2025 report (released Nov 5) was a mixed bag. The company posted quarterly revenue of $5.2 million, a steep drop from $26.1 million in Q3 last year [13]. This was a significant miss versus Wall Street’s ~$17 million forecast, reflecting the lumpy nature of partnership payments (no big milestone was booked as revenue in Q3) and the absence of any product sales [14]. Meanwhile, expenses surged after the late-2024 merger with Exscientia (more on that below): R&D costs jumped to $121.1 million (vs $74.6 M a year ago) and the net loss deepened to $162.3 million in the quarter [15] [16]. The widening loss underscores the heavy investment in pipeline and technology integration.
On the positive side, Recursion achieved a notable R&D milestone that validates its platform. Roche and Genentech accepted Recursion’s novel whole-genome “Microglia Map” (a sophisticated atlas of brain immune cells) as part of their collaboration, triggering a $30 million payment to Recursion [17] [18]. This is the second such neuroscience milestone hit under the Roche/Genentech alliance and brings Recursion’s cumulative partner payments to over $500 million to date [19] – an almost unprecedented haul for a pre-commercial biotech. Management noted this achievement “underscores the strength of [Recursion’s] partnership strategy” and provides external validation of its AI-driven approach [20] [21]. Notably, Recursion expects up to $100 million more in potential milestone payouts by 2026, which would further bolster its finances [22].
CEO Transition: In a major leadership move, Recursion’s board unanimously approved a CEO succession plan to position the company for its “next phase of growth.” Co-founder and current CEO Chris Gibson will transition to Chairman of the Board, and Dr. Najat Khan – Recursion’s Chief R&D and Commercial Officer – will become the new CEO and President effective Jan 1, 2026 [23]. Dr. Khan joined Recursion in 2024 (coming from a senior data science role at J&J) and has been instrumental in guiding the pipeline and the Exscientia merger [24]. The planned handoff is portrayed as a natural evolution: Gibson led Recursion for 12 years from a scrappy startup to a public “TechBio” pioneer, and now Khan will lead the company’s execution-focused next chapter [25] [26]. Investors generally view Khan as a highly capable leader with both scientific and business acumen – she’s credited with helping scale AI efforts at J&J and driving Recursion’s recent strategic moves [27] [28]. The market’s initial reaction to the announcement was mixed; RXRX stock was down modestly (~1–2%) in pre-market trading after the news [29], likely reflecting the broader recent downtrend rather than a vote of no confidence. Overall, the transition appears well-planned and is expected to be smooth, with Gibson staying actively involved as Executive Chairman in 2026 [30] [31].
Other Updates: It’s worth noting that just a few months earlier, in June 2025, Recursion undertook a strategic restructuring amid a tough biotech funding environment. The company laid off ~20% of its workforce (around 160 employees) to streamline operations and extend its cash runway [32]. Management refocused the pipeline on key programs (especially in oncology and rare diseases) and shelved a few early-stage projects that had shown weak data [33]. This difficult step was part of “reducing complexity… so that every dollar drives real ROI” in a capital-constrained market, according to CEO Gibson [34]. The silver lining: by cutting costs, Recursion projected it could keep 2025 cash burn under $450 M and 2026 under $390 M, extending its runway into late 2027 [35]. Indeed, as of Q3, the company confirms it has cash to fund operations through 2027 without needing new funding [36] [37]. These moves, combined with milestone inflows, have eased near-term financing concerns – a critical factor for investor sentiment in high-burn biotechs.
Stock Price and Trading Activity (Nov 5, 2025)
Recursion’s stock (RXRX) has been on a rollercoaster in 2025, reflecting both company-specific events and broader biotech market swings. As of Nov 5, 2025, RXRX trades around $5.00 per share, roughly the same level it closed at on Nov 4 [38]. This price is down about 8% from a week ago and ~15% over the past week or so [39], a drop likely attributable to pre-earnings jitters and broader market volatility. Notably, on Nov 4 the stock fell −8% in heavy trading to $5.00 [40], suggesting traders were bracing for the underwhelming earnings results or reacting to rumors of the CEO change (which was officially announced the next morning).
Despite recent declines, RXRX is well above its 2025 lows. Earlier in the year, the stock dipped near its 52-week bottom around $4 amid a biotech slump [41]. It then saw a strong rally to the mid-$6 range by late October, partly on anticipation of partnership milestones and a general bounce in AI-related stocks. In fact, Recursion’s stock has a history of sharp spikes when positive news hits. A year ago (Nov 2024), shares jumped above $6 after the merger with Exscientia was completed. And famously in mid-2023, Recursion stock surged 83% in one day when NVIDIA announced a $50 million investment and collaboration – RXRX hit ~$12.40 at that time, its all-time high [42] [43]. That spike illustrated the hype around AI drug discovery, though the gains proved hard to hold as the company’s long timelines became clear.
Currently, Recursion’s market capitalization is about $2.2–2.5 billion, and the stock’s 52-week range is roughly $3.97 – $10.87 per share [44]. Trading volume spiked on Nov 4–5 around the earnings release, indicating active interest from traders and possibly short-sellers closing positions. (RXRX has attracted some attention as a potential short squeeze candidate in the past, given its high short interest and volatile news cycle [45], but so far no GameStop-like scenario has occurred.) After the recent pullback, the stock is hovering just below its 50-day moving average (~$5.2) and well below the 200-day average (~$5.8) [46]. Technical traders may view the $5 level as a support zone, with upside resistance around $6–$7 (where the stock traded before the Q3 drop). Overall, market sentiment on RXRX in late 2025 is cautiously optimistic: the stock has underperformed many biotech peers recently, yet it remains “in play” thanks to Recursion’s unique AI story and upcoming catalysts.
Business Model: AI-Driven Drug Discovery Platform (Recursion OS)
Recursion Pharmaceuticals is often described as a “TechBio” company – essentially a biotech that operates like a tech firm. The heart of its business model is the Recursion OS, an AI-driven drug discovery platform that combines massive experimental biology with cutting-edge machine learning. Rather than relying on traditional trial-and-error lab science alone, Recursion generates huge datasets from high-throughput automated experiments and then uses advanced algorithms to uncover patterns and novel therapeutic insights.
At its core, Recursion’s platform conducts “phenomic” screening: the company has automated laboratories running up to millions of cell-based experiments each week, perturbing cells with thousands of compounds or genetic edits and imaging the results [47]. These image-based phenotypic datasets – along with chemistry and -omics data – feed into Recursion’s proprietary database, which is one of the world’s largest in biotech at over 60 petabytes (60 million gigabytes) after the Exscientia merger [48]. Recursion then applies sophisticated machine learning models to this trove of data to map relationships between genes, proteins, and small molecules. According to the company, its AI has distilled “trillions of searchable relationships across biology and chemistry, unconstrained by human bias” [49]. In practical terms, this means the platform can identify unexpected drug-target interactions or disease pathways that a human scientist might never hypothesize.
To power this AI-first approach, Recursion invested heavily in computing infrastructure. In fact, Recursion (in partnership with NVIDIA) built what is claimed to be the largest supercomputer in the pharmaceutical industry [50]. Completed in 2024, this supercomputer (cluster of GPU servers) gives Recursion an edge in training large-scale models and running simulations. It enables initiatives like Recursion’s collaboration with MIT on Boltz-2, an AI model to predict molecular binding affinities at unprecedented speed [51]. The company also leverages cloud computing (through NVIDIA’s platforms) to share certain AI models with partners [52]. Importantly, Recursion’s vision includes eventually creating “virtual cells” – high-fidelity computational replicas of human cell behavior – which could allow in silico drug testing at massive scale [53]. While that is still aspirational, these capabilities illustrate why Recursion is often mentioned in the same breath as tech giants when talking about AI in medicine.
In summary, Recursion’s business model is to industrialize drug discovery. By uniting biology, chemistry, robotics, data science, and AI (all in-house), Recursion aims to dramatically shorten the R&D timeline and reduce costs for new medicines. This is tackling a well-known industry pain point: developing a single new drug can take 10+ years and cost over $1 billion, with a very high failure rate in Phase 3 trials [54]. Recursion’s approach – testing compounds on virtual cell models, using AI to predict best hits, and even optimizing clinical trial design – aspires to flip that paradigm [55] [56]. It’s essentially a full-stack drug hunter, combining wet-lab and dry-lab innovation. If successful, Recursion could find and develop drugs faster (potentially in 2–3 years for lead optimization instead of 5–7 [57]) and do so across many disease areas in parallel. This model has attracted considerable interest from big pharma partners and tech investors (more on partnerships next), though it remains unproven in terms of yielding an approved drug.
Pipeline Progress and R&D Status
As of late 2025, Recursion’s internal pipeline includes over 10 programs spanning clinical and preclinical stages [58] [59]. However, it’s important to note that none of Recursion’s drug candidates have reached Phase 3 (late-stage trials) or received FDA approval yet. The company’s most advanced projects are in Phase 2 or Phase 1 – meaning any potential product revenue is still years away. This lack of near-term clinical success is a key risk factor frequently cited by analysts [60] [61].
Some highlights of Recursion’s pipeline:
- REC-994 – A Phase 2 candidate for Cerebral Cavernous Malformation (CCM, a rare neurovascular disorder). This is one of Recursion’s earliest programs and has been in mid-stage trials to assess efficacy in preventing brain vessel malformations [62]. An update is expected in 2025 on whether REC-994 showed signals of benefit; results will determine if it advances to Phase 3 or not.
- REC-2282 – A Phase 2 program for Neurofibromatosis type 2 (NF2, a rare tumor syndrome). This was originally an Exscientia-developed asset that Recursion took on. A futility analysis was due in H1 2025 [63]; although results haven’t been formally detailed in press releases, there are reports that the outcome was not compelling, contributing to Recursion’s decision to deprioritize or halt this program in mid-2025 [64]. The pipeline reprioritization in June suggests REC-2282 and a couple of other less promising projects were axed after weak data, allowing resources to shift to higher-upside programs [65].
- REC-4881 – A Phase 2 trial in Familial Adenomatous Polyposis (FAP, a hereditary cancer syndrome). This is a MEK inhibitor that Recursion in-licensed from Takeda, now being tested in the TUPELO study. Encouragingly, Recursion expects additional data in Dec 2025 for REC-4881 in FAP [66] [67]. This upcoming readout is a near-term catalyst; positive results could not only validate the Recursion OS-driven approach to repurposing drugs but also attract investor interest as a potential path to Phase 3.
- REC-617 – A Phase 1/2 trial for advanced solid tumors (a CDK7 inhibitor for cancer). Recursion reported in Q3 that REC-617’s Phase 1 dose-escalation established a tolerable dose and showed preliminary anti-tumor activity (including at least one partial response) [68] [69]. They’ve now expanded into a combination-therapy cohort for ovarian cancer. This program is significant because it was “precision-designed” using Recursion’s AI (not just a standard oncology drug), so any hint of efficacy bolsters the AI-designed drug thesis.
- REC-7735 – A preclinical candidate targeting a specific PI3Kα mutation (H1047R) in cancers. This compound was discovered by Recursion’s AI platform and has shown impressive tumor regression in models while sparing normal PI3K activity [70]. Recursion just nominated REC-7735 as a development candidate and aims to start Phase 1 in 2026 [71] [72]. If it lives up to “best-in-class” potential in mutants, it could be a valuable asset (e.g., in breast cancer with that mutation).
Beyond these, Recursion has multiple early-stage programs (some inherited from Exscientia) targeting oncology, immunology, and rare diseases. The combined pipeline after merging Exscientia featured 10+ programs in discovery in addition to those above [73] [74]. The company has indicated several new INDs (Phase 1 starts) are expected in 2025–2026 [75], including REV-102 for hypophosphatasia (an enzyme deficiency) and REC-1245 (an RBM39 degrader for cancer). However, Recursion is also being disciplined in pipeline focus – in 2025 they halted at least three projects after data disappointments (to “regain investor faith” by focusing on winners) [76]. This culling was seen as a necessary step to concentrate on programs with the highest chance of success like REC-4881, REC-617, etc.
The big picture: Recursion’s pipeline is rich and varied, but still unproven in the clinic. The company’s value is tied less to any single drug and more to the productivity of its platform across many shots on goal. Investors should watch upcoming readouts (like the FAP trial data in Dec 2025) and early human data from the AI-designed compounds. If Recursion can demonstrate a clear clinical win – e.g. a Phase 2 success that leads to a partnership or Phase 3 start – it would be a watershed moment for confidence in the Recursion OS. Until then, the pipeline contributes to the story (and does have tangible value: the partnerships on these programs have already brought in significant cash), but it also underpins the “no tangible proof of success – yet” caveat on the stock [77].
Financial Performance and Outlook
Despite being pre-revenue (no product sales), Recursion has managed to sustain a strong financial position through partnerships and financing – but it continues to incur large losses as it invests in R&D. Here are key financial highlights:
- Revenue: In 2025, Recursion’s revenues are entirely from collaboration payments (milestones, upfronts) and some grants. Q3 2025 revenue was $5.2 M, down sharply from $26 M in Q3 2024 (which had included a big Roche milestone) [78]. For the first nine months of 2025, total revenue was ~$39 M [79]. The miss in Q3 was notable – $4.98 M vs $17 M expected [80] – because the anticipated Roche payment only came in October and will be recognized in Q4. Looking ahead, revenue is inherently lumpy and hard to predict, as it depends on deal timing. The company anticipates ~$100 M in additional milestone revenue by end of 2026 [81], which, if realized, would be a meaningful influx. However, absent new partnerships or milestones, baseline revenue from existing deals is relatively modest (single-digit millions per quarter).
- Expenses and Earnings: Recursion’s operating costs are very high, reflecting its ~800 staff (pre-layoffs) and dual wet/dry labs. In Q3 2025, R&D expense was $121.1 M (up +62% YoY) and G&A expense $41.6 M [82]. The surge partly comes from absorbing Exscientia’s operations (the merger closed Nov 2024) and one-time IPR&D asset purchases [83]. Even after June’s layoffs, quarterly burn remains substantial. Consequently, net loss in Q3 was $162.3 M, nearly double the $95.8 M loss a year prior [84]. On a per-share basis, RXRX lost about $0.36 per share in Q3 (wider than estimates of ~$0.33 loss). For full-year 2025, the company’s loss will likely exceed $500 M. These figures underscore why Recursion’s EPS is deeply negative (trailing EPS around –$1.80 [85]) and why traditional valuation metrics (P/E, etc.) aren’t meaningful yet [86].
- Cash Runway: On the positive side, Recursion has amassed an unusually large cash reserve for a company at its stage. As of October 9, 2025, the company held approximately $785 M in cash and equivalents [87]. This was boosted by a $388 M equity ATM offering that Recursion smartly completed in Q3/Q4 2025, selling shares into market rallies (such as the NVIDIA news spike) [88]. With this war chest, Recursion projects it can fund operations through end of 2027 without needing additional financing [89] [90]. This 4+ year runway is a huge strategic asset in biotech – it means Recursion can be patient and isn’t forced to dilute shareholders or cut crucial programs in the near term. It also provides leverage in partnership negotiations, since the company isn’t desperate for cash. That said, if the opportunity arises, Recursion could still raise more capital opportunistically (e.g. via partnerships or tech licensing deals) to further extend its runway.
- Balance Sheet: Beyond cash, Recursion has minimal debt (if any) and a clean balance sheet following the Exscientia merger. Goodwill from the merger and acquired intangibles exist, but those are long-term considerations. The company’s equity base is strong – notable investors include ARK Invest (Cathie Wood’s fund), Baillie Gifford, and even the UK government via its Future Fund (inherited from Exscientia’s investor base) [91] [92]. These holders indicate confidence in the long-term story.
In summary, Recursion’s financial situation can be viewed as “cash-rich but earnings-poor.” It has sufficient cash to execute its R&D strategy for several years (a rarity among clinical-stage biotechs), thanks to savvy capital raises and partner money. However, the company will likely continue running large losses for the foreseeable future – Recursion itself guided to ~$450 M operating burn in 2025 excluding one-offs [93]. The hope is that these investments pay off in the form of successful drugs or lucrative partnership outcomes down the line. For now, investors must accept that profitability is years away; the focus is on milestones (both scientific and financial) as value-inflection points rather than traditional earnings metrics. As one analysis bluntly put it, “Recursion’s lack of clinical success makes the stock very risky for investors now” [94] – the implication being that the company’s immense spending must eventually yield tangible results (approved drugs or significant licensing deals) to justify itself.
That said, the company’s milestone achievements already show some ROI on its platform: over $500 M earned from Roche, Sanofi, and others to date [95] [96], with billions more possible in future milestones. These partnerships, covered next, effectively subsidize Recursion’s R&D and validate its approach financially. Many biotech startups never secure this level of external funding, so it’s an encouraging sign on Recursion’s financial journey.
Partnerships, Collaborations, and Notable Deals
One of Recursion’s greatest strengths – and a key differentiator among AI-biotech companies – is its roster of major partnerships with both pharmaceutical giants and technology leaders. These collaborations provide non-dilutive capital, drug development expertise, and additional data that feed the Recursion OS. Here are the most significant partnerships and deals:
- Roche & Genentech (Neuroscience and Oncology): In 2021, Recursion entered a landmark collaboration with Roche (and its U.S. biotech arm Genentech) to leverage Recursion’s platform for discovering new treatments in neuroscience and gastrointestinal cancer. This is a 10+ year alliance covering up to 40 programs [97]. Roche paid significant upfronts and has been making milestone payments as Recursion delivers on defined R&D objectives. To date, Recursion has received $213 M from the Roche partnership [98] – including the two $30 M “phenomap” milestones for mapping cell biology (one in August 2024 and one in Oct 2025) [99] [100]. Roche also optioned its first drug program from Recursion’s outputs (a GI oncology target) and is evaluating others [101]. In total, this deal could exceed $300 M per program in milestone payouts (over $12 B across all programs if every target succeeds) [102], plus royalties [103]. The Roche partnership is a strong validation of Recursion’s platform in big pharma’s eyes – Roche is essentially betting on Recursion’s AI to help fill its pipeline in complex diseases like Alzheimer’s and autism. It’s also notable that Roche expanded the deal in 2022 to include neuroscience after initial results, showing Roche’s continued confidence [104]. For Recursion, Roche’s deep pockets and expertise in drug development are invaluable; the collaboration not only brings cash but also guidance on advancing programs to the clinic.
- Sanofi (Multi-Target Deal in Oncology/Immunology): In 2022, Recursion signed a multi-year collaboration with Sanofi to discover drugs for up to 15 new targets in cancer and immunology. Sanofi paid $150 M upfront and has since paid Recursion around $130 M in milestones so far [105] (including a $7 M milestone in mid-2025 for hitting a discovery goal [106]). Each program under this deal carries over $300 M in potential milestones for Recursion, plus royalties [107]. Sanofi has been actively utilizing Recursion’s platform (Recursion OS 2.0 including the phenomics + Exscientia’s design tools) to feed its pipeline [108]. This partnership underscores that multiple top pharma companies see Recursion as a valuable drug discovery engine. With Sanofi, Recursion is focusing on hard problems in oncology/immunology, aiming to deliver “first-in-class or best-in-class” therapeutic candidates [109]. Achieving even a couple of clinical successes here could be transformative for Recursion (and very lucrative via milestones). Sanofi’s continued engagement (they have several joint programs advancing toward lead status as of Q3 2025 [110]) suggests the collaboration is bearing fruit.
- Merck KGaA (Exscientia’s Collaboration): Through the Exscientia acquisition, Recursion inherited a partnership with Merck KGaA (Darmstadt, Germany). Announced in Sept 2023, this deal uses Exscientia’s (now Recursion’s) AI capabilities for precision drug design on certain Merck targets [111]. The multi-year collaboration could be worth up to €500 M+ in milestones (over $1 B) to Recursion if all goals are met [112]. While details are scarce, Merck KGaA’s involvement further validates Recursion’s platform on a global scale. It shows Recursion can attract European pharma as well, expanding its reach. Any progress or candidate nominations from this partnership would be incremental wins.
- Bayer: Another big name tied to Recursion is Bayer AG. Bayer was listed among the “world’s largest pharma companies” that have deals with Recursion [113]. In fact, Reuters reported that Recursion’s “current partners include Bayer and Roche” as of mid-2023 [114]. The Bayer relationship likely originated through Exscientia, which had a 2020 AI drug discovery collaboration with Bayer in cardiovascular and oncology domains. The status of that collaboration isn’t publicly updated, but it presumably continues under Recursion’s umbrella. Bayer’s inclusion in Recursion’s partner ecosystem signals broad pharma interest; even if no milestone news from Bayer has been announced recently, having such an industry leader engaged is a vote of confidence in Recursion’s technology.
- NVIDIA (Tech Alliance & Investment): In July 2023, Recursion struck a headline-grabbing partnership with NVIDIA, the AI computing giant. NVIDIA made a $50 M equity investment in Recursion [115] (buying about 4% of the company’s stock [116]) and agreed to collaborate on developing AI foundation models for drug discovery. Recursion is using NVIDIA’s cloud and GPU infrastructure to train its models on an unprecedented scale (it has >23,000 terabytes of proprietary data to feed in [117]), and NVIDIA can in turn license the resulting models to other biotech/pharma via its BioNeMo AI service [118]. This is a win-win: Recursion gets cash, compute power, and validation from the premier AI hardware player; NVIDIA gets a stake in Recursion and high-quality biomedical data to enhance its AI offerings. This collaboration also produced the aforementioned ultra-powerful supercomputer that Recursion now uses [119]. The NVIDIA deal exemplifies the convergence of tech and pharma – it’s “forging the future together,” as industry watchers note [120]. For investors, NVIDIA’s backing was a major credibility boost for Recursion’s AI bona fides (hence the huge stock surge on the news). It suggests Recursion is seen as a leader in applying AI at scale in life sciences, enough to attract top-tier tech money.
- Other Notable Deals: Recursion’s partnerships extend further: prior to merging with Recursion, Exscientia had collaborations with firms like Celgene/BMS (in oncology) and GSK (in antiviral drug design). Some of those yielded early drug candidates (for example, Exscientia delivered a compound to Celgene that was later reclaimed and is being developed in-house). It’s unclear if those are ongoing, but they contribute to Recursion’s legacy of partner-engaged projects. Recursion is also part of the Camp4 Collaborative and has data-sharing arrangements with genomics/diagnostics companies like Helix and Tempus to enrich its datasets [121]. Additionally, Recursion has alliances with academia (e.g. University of Utah, where it started, and MIT CSAIL as mentioned).
In total, Recursion’s partnered programs now number 10+ (across Roche, Sanofi, Merck, etc.) and have already brought in about $450 M in upfront/milestone payments [122] [123]. More than $20 B in future milestone payments are theoretically on the table across all deals [124] – a staggering figure illustrating the scale of Recursion’s opportunity if its AI discoveries pan out. These partnerships not only validate Recursion’s tech, they also effectively outsource a chunk of R&D costs to deep-pocketed partners. As Finimize aptly noted, “milestone payments and partner funding offer critical validation… and much-needed financial breathing room” in this high-risk sector [125] [126].
Expert Commentary and Market Sentiment
The narrative around Recursion Pharmaceuticals is one of great promise tempered by significant uncertainty. Here’s what expert commentators and analysts are saying, in summary:
- High Potential, High Risk: Investment writers often describe Recursion as a “speculative long-term wager” in the AI-biotech space [127]. Forbes noted that despite notable share price volatility (down ~27% YTD by mid-2025), Recursion continues to attract interest for its innovative approach [128]. However, the lack of any approved drugs means the stock’s fortunes hinge on faith in the platform and distant outcomes. The Motley Fool bluntly stated that Recursion’s “lack of clinical success makes the stock very risky for investors now.” [129] They highlight that until Recursion proves it can actually develop a drug that works, skepticism will persist. In The Motley Fool’s “3 Things to Know” piece (Nov 4, 2025), the author emphasized that Recursion has the largest AI supercomputer in biotech and big-name partners, but “no tangible proof of success – yet.” [130] [131] It’s a classic case of potential versus proof.
- Analyst Ratings: Wall Street analysts are generally cautiously optimistic. According to one stock analysis, there are 2 “Buy” and 6 “Hold” ratings on RXRX, and no outright Sell ratings [132]. The average price target is around $6.50 – only slightly above current levels [133]. This suggests analysts see some upside, but not a dramatic surge in the next year, reflecting a wait-and-see stance. Finimize noted that analysts maintain a Hold consensus and a median target ~23% above the current price [134], which implies confidence in Recursion’s strategy but acknowledgment of near-term challenges. In earnings calls, analysts often probe Recursion’s management on when we might see tangible pipeline wins or monetization of the AI platform beyond partnerships. The sentiment is essentially: “We like the technology and deals, but show us progress in the clinic.”
- Market Sentiment & Comparisons: Within the biotech sector, Recursion’s recent stumbles (revenue miss, program cuts) stand out against some peers that have had smoother progress. As Finimize pointed out, many biotech rivals still garner “Buy” ratings and have had upbeat results in 2025, whereas Recursion’s underwhelming Q3 and pipeline resets have made observers more cautious [135]. That said, the sector backdrop is improving (biotech indices have been recovering in late 2025), and Recursion’s big cash buffer means it’s “far from out of the running.” [136] If anything, the AI drug discovery theme remains a hot topic – Recursion is frequently cited alongside others like Schrodinger and Insilico as leaders in this nascent field. There is a sense that some AI-biotech will eventually deliver breakthroughs, and Recursion is a top contender, but investors are trying to discern if Recursion will enjoy a first-mover advantage or suffer from first-mover costs.
- Cathie Wood & ARK’s View: Notably, Cathie Wood’s ARK Invest has been a recurring buyer of Recursion stock, viewing it as an AI + biotech convergence play. Wood has spoken bullishly about Recursion’s approach to “industrialize drug discovery” and the fact that it combines AI with real-world lab science (giving it a moat of proprietary data) [137] [138]. ARK’s Genomic Revolution fund (ARKG) has held RXRX, and ARK even bought additional shares on dips in 2024–2025 [139]. This endorsement from a high-profile tech investor contributes to positive sentiment among growth-oriented investors. However, traditional biotech investors may be more skeptical, noting that Recursion’s market cap (over $2 B) is “pricing in” a lot of future success already. For context, some analysts compare Recursion to a software company in valuation, given its lack of revenue – a dynamic that can lead to high volatility as sentiment swings.
- Competitive Landscape Commentary: Experts also discuss Recursion in the context of growing competition. The NAI 500 article “Beyond the Tech Titans” (Nov 4, 2025) cautioned that “rival Eli Lilly recently announced plans to team up with NVIDIA to construct an even larger supercomputer – directly challenging Recursion’s core tech advantage.” [140] Indeed, big pharmas are not standing still; many are investing in AI internally or via deals (e.g., Lilly’s collaboration with Schrödinger and AI cloud initiatives). This means Recursion must continue to innovate to stay ahead. The same article praised Recursion’s partner network and early bet on AI, but underlined “no approved drugs and intensifying competition from well-funded rivals” as reasons the company has a “high-risk profile.” [141] [142]. In short, while Recursion has a head start, it’s no longer alone in the AI-drug race – something investors are watching closely.
- Sentiment on Cash & Runway: A positive theme in commentary is Recursion’s strong cash position and extended runway. As mentioned, this eases near-term worries of dilution or insolvency [143]. It also provides a comfort buffer for analysts who otherwise might be very concerned about the company’s burn rate. The fact that Recursion pro-actively raised cash at opportune times (e.g., ATM offering when stock popped) shows management is financially savvy. Some commentators even suggest Recursion’s cash could allow it to acquire complementary technologies or smaller biotechs to further bolster its platform (similar to how it bought Cyclica and Valence in 2023). So there is an undercurrent of “they have the resources to execute if anyone can.”
Overall, market sentiment on Recursion is mixed-positive: there’s genuine excitement about the paradigm-shifting potential (Recursion is often cited as “an AI stock with a different kind of disruption” [144]), but also a clear-eyed understanding that the company needs to prove its model in practice. As one outlet quipped, Recursion represents “the future of pharmaceuticals?” – maybe, but it’s a long road to get there. For now, investors are watching milestone by milestone, and the stock’s performance will likely track those successes or setbacks in the coming quarters.
Technical Analysis and Stock Chart Trends
From a technical stock-chart perspective, RXRX has been trading in a wide range and exhibiting high volatility – typical of a clinical-stage biotech intertwined with AI hype. Here are some key technical observations:
- Volatility & Range: Over the last 12 months, RXRX swung between a low of about $3.97 and a high of $10.87 [145]. That range reflects multiple boom-bust cycles: a surge in mid-2023 (NVIDIA news), a pullback, another rally post-Exscientia merger in late 2024, and declines in early-mid 2025 during the biotech downturn. Such volatility (270% from low to high) indicates that Recursion’s stock is highly sensitive to news and sentiment shifts. Traders have been able to “ride the waves of biotech innovation” with this stock [146], but timing is everything.
- Moving Averages: As of early Nov 2025, RXRX sits below its longer-term trend lines. The 50-day moving average is around ~$5.20 and the 200-day MA around ~$5.75 [147]. After the recent earnings-related drop, the stock fell under both, suggesting near-term momentum turned bearish. However, prior to that, in October the stock had broken above the 200-day MA for the first time in months, which was seen as a bullish sign until the rally fizzled. These averages will act as resistance levels on any rebound – the stock would need to clear $5.20 then $5.75 with strong volume to convince technical traders that a new uptrend is forming. On the downside, if the stock revisits the low-$4’s, that corresponds to the previous 52-week low region, which could act as support (and also where value-oriented buyers like ARK stepped in historically).
- Relative Strength Index (RSI): The RSI for RXRX was recently around 40–45, which is slightly on the low side but not extreme [148]. (An RSI below 30 would indicate oversold conditions). After the week of declines, the stock might be approaching oversold territory, but not quite there. This suggests there could be some room for further decline before hitting technical bottom, unless a positive catalyst emerges to reverse momentum.
- Chart Pattern: The chart in 2025 could be interpreted as a broad sideways consolidation with a slight downtrend bias. After the sharp drop in Q1 2025 (post-ARK hype cooldown and biotech slump), RXRX traded roughly between $4 and $6 for most of the year. There were a few breakout attempts – e.g., it spiked to ~$7 in Feb 2025 on an AI news wave, and again to ~$6.50–$7 in Sept 2025 possibly on rumors of data milestones. But each time, it fell back into the range. This range-bound action indicates neither bulls nor bears have dominated for long; instead, news flow has dictated short-term swings. The absence of a sustained trend suggests traders are waiting for a clearer fundamental signal (like trial results or big partnership news) to drive the next sustained move.
- Volume & Squeeze Potential: Volume spikes have coincided with news events. Notably, 40+ million shares traded on Nov 4, 2025 when the stock dropped 8% [149] – this hints at either a large holder exiting or a flurry of short selling ahead of earnings. RXRX’s float is considerable (after the Exscientia merger and ATM issuance, shares outstanding are large), so it takes significant news to move it drastically now. Short interest has been relatively high (somewhere in the 10–20% of float range at times, per market reports), leading Benzinga to list Recursion among stocks that short-sellers watch for squeezes [150]. If Recursion delivered unexpectedly great news (say a trial breakthrough), the stock could see a short-covering rally. Conversely, in the absence of news, shorts have been able to profit from the company’s steady cash burn and dilutive share issuances (like the ATM).
- Key Levels: To the upside, $6.00–$6.50 is a notable resistance zone – that’s where the stock topped out in late 2024 and again in late summer 2025. Beyond that, the $8–$9 region would be another target (this was a support area in mid-2023 on the way down). On the downside, aside from the ~$4.00 floor from last year, if that broke, the next psychological level would be $3.50 (not seen since early 2022 post-IPO). But given Recursion’s cash per share is around $3–4, many traders view mid-$4’s as a floor of fundamental support (it’s rare for a well-funded biotech to trade near cash unless prospects are dire).
In technical summary, RXRX is in a holding pattern, oscillating with news and sentiment. The stock’s long-term trajectory will ultimately follow fundamentals (clinical and business progress), but in the near term, technical traders can expect continued choppiness. With moderate RSI and the stock near support, we could see a bounce from ~$5 if any positive catalyst emerges. Conversely, lacking news, the stock may drift lower to test prior lows. Investors should be prepared for significant volatility, which is par for the course in an early-stage biotech that also has the volatility profile of an AI tech stock.
Forecasts and Outlook
Short-Term (Next Few Weeks to Months)
In the short term, the outlook for RXRX will hinge on a few upcoming events and the broader market mood for biotech/AI stocks:
- Upcoming Catalysts: A key near-term catalyst is expected in December 2025, when Recursion will reveal additional data from the Phase 2 TUPELO trial of REC-4881 in FAP (Familial Adenomatous Polyposis) [151]. If this data shows meaningful efficacy or safety signals, it could boost the stock, as it would mark one of Recursion’s first internal programs demonstrating patient benefit. Positive data might also pave the way for partnering that program or advancing to Phase 3, either of which would be bullish. Conversely, lackluster results could weigh on shares, reinforcing the “no clinical proof” bear thesis. Aside from REC-4881, any new partnership announcements or additional milestone achievements in Q4 2025 would be short-term positives. For instance, Roche or Sanofi picking another program to advance (triggering a payment), or Merck expanding its collaboration, would generate good news flashes.
- Earnings & Guidance: When Recursion reports its Q4 or full-year 2025 results (likely in Feb 2026), investors will watch for updates on cash burn and any guidance on 2026 milestones. Management’s commentary on the CEO transition (as Dr. Khan takes over) and strategic priorities will also set the tone. If they indicate further cost discipline or narrower focus (beyond the June cuts) to extend runway even more, that could be well-received. On the flip side, any hint of needing new financing before 2027 (which is not expected given current cash) would be a negative surprise.
- Market Environment: Broadly, the biotech sector sentiment is improving in late 2025 after a rough 2022–2023. Interest rates stabilizing and a risk-on appetite for tech/AI plays have helped biotech indices rebound. If this “risk-on” wave continues into early 2026, RXRX could benefit as part of the AI-in-healthcare narrative. However, if there’s a market pullback or renewed aversion to money-losing companies, Recursion’s stock could struggle in sympathy. Keep an eye on indices like XBI (biotech ETF) and notable peers – if they rally, RXRX often tags along, and vice versa.
- Trading Range Expectation: Barring major news, RXRX might remain range-bound in the next few weeks, roughly between $4.50 and $6.00. A significant catalyst (like strong trial data or a new deal) would be needed to break above $6 with conviction. Conversely, it likely would take a big disappointment to break below $4, given the fundamental support of cash and partnerships. Short-term traders may attempt to swing trade these levels.
In summary, the next few weeks for Recursion are about event-driven moves: all eyes on the December trial data, any year-end partnership updates, and the general biotech investing climate. The short-term forecast can thus be characterized as “cautiously optimistic volatility.” Expect swings around news, but a transformative breakout (up or down) likely requires clear scientific or commercial signals which might still be a quarter or two away.
Long-Term (1–5 Years)
Looking out over the next 1 to 5 years, the fate of Recursion Pharmaceuticals will be determined by its ability to turn its AI-powered discoveries into real-world drugs and/or high-value partnerships. Here are some longer-term forecast considerations:
- Pipeline Milestones: In a 1–2 year view (through 2026–2027), Recursion should have multiple Phase 2 readouts and possibly a couple of programs entering Phase 3 trials if things go well. For example, if REC-4881’s upcoming data is positive, a pivotal Phase 3 could start by 2026, meaning potential FDA approval around 2028. REC-617 could also advance to a Phase 2b/3 in a specific cancer if early results hold up, etc. The first approved drug originating from Recursion’s pipeline is the “holy grail” – even the prospect of a Phase 3 success could re-rate the stock significantly upward (biotechs often see major appreciation when they transition from early-stage to late-stage with a viable product). However, if in 2–3 years Recursion still hasn’t produced any late-stage candidates or if trials disappoint, the stock could languish or decline as patience runs thin.
- Partnership Outcomes: In the 1–5 year horizon, some of Recursion’s partnered programs with Roche or Sanofi are likely to reach decision points. Roche, for instance, could advance more programs into the clinic; if any hit proof-of-concept, Roche might exercise options or even consider acquiring Recursion to secure the platform (a speculative but not implausible scenario if Recursion’s tech proves extremely valuable). Similarly, Sanofi or Merck might deepen ties if results are promising. Each partnered success would bring milestone payments (potentially hundreds of millions each) – even a handful of those by 2027 would substantially boost Recursion’s financial position and credibility. Conversely, a risk is that big partners could walk away if the AI-generated candidates underperform. If, say, Roche’s programs fail to produce viable drug leads, they might discontinue the alliance (though no such signs yet). The long-term stock trajectory will weigh these partnership “verdicts.”
- Financial Trajectory: With the current cash, Recursion is funded into 2027. By then, if things go well, the company might either be on the cusp of its own product revenue or flush with new milestone cash – ideally offsetting the burn. Analysts will be modeling whether Recursion needs to raise capital again in the later 2020s. Dilution risk is moderate in the long-term: if the stock remains low and no large new deals come, Recursion might eventually need a raise post-2027. But if milestone income flows in and the stock price improves, they could finance in a less painful way or not at all. Many expect Recursion’s cash burn to start decreasing by 2026–2027 as the merged entity finds efficiencies and focuses spending on fewer, most promising programs (management guided to lower burn in 2026 vs 2025 [152]). Achieving those burn reduction targets will be important for long-term valuation – showing a path to sustainability.
- Stock Price Targets: Long-term price forecasts for a company like Recursion are highly speculative. The current average analyst 12-month target is ~$6–7 [153], but looking 5 years out, the range of outcomes is huge. Bull case: Recursion’s platform yields multiple successful drugs, at least one approval or pivotal trial by 2030, plus continuous partner deals – in this scenario, Recursion could be a multi-bagger from today’s price, potentially reaching a market cap in the tens of billions (comparable to a mid-size pharma) if it proves an ability to consistently create new medicines. ARK Invest and other growth investors likely envision this kind of “transformative winner” scenario, where Recursion becomes the de facto leader of AI in pharma and captures enormous value (Cathie Wood has hinted at such upside, citing AI medicine as a frontier). Bear case: The platform fails to deliver meaningful drugs, partnerships fizzle out, and cash eventually dwindles – in which case the stock could erode, possibly trading near cash value or being acquired cheaply for its data. A middle-ground scenario is that Recursion achieves some success, but at a slower pace – maybe one mid-level drug approval by 2029 and a steady but not explosive business. In that moderate scenario, the stock might drift modestly upward, perhaps in the $5–10 range over years, tracking incremental progress.
- Competitive Landscape: Over five years, Recursion will face increasing competition from both startups and big pharma’s own AI efforts. By 2030, AI-driven drug discovery might be mainstream, and Recursion will need to maintain its edge. One long-term advantage Recursion has is its massive proprietary dataset (which grows every week). Data can compound into a moat. Also, by merging with Exscientia, Recursion removed one key competitor and absorbed its capabilities. Still, companies like Schrödinger (SDGR), which applies physics-based and machine learning methods, or Insilico Medicine (private, but advancing AI-designed drugs into Phase 2), will be vying for the title of AI drug discovery leader. Traditional pharma companies might also develop in-house AI platforms rivaling Recursion OS. So far, though, Recursion’s strategy of partnering with pharma rather than against them has been smart – it integrates itself into the ecosystem. Long-term investors will watch if Recursion continues to strike new partnerships (perhaps with additional pharma companies) – a new marquee partner in the coming years (e.g., a Pfizer or Novartis signing on) would be a bullish sign of relevance in 2028+.
- Acquisition Wildcard: It’s worth noting the possibility that Recursion could be acquired in the next 5 years if a big pharma decides its platform is too valuable to leave independent. Large pharmas have acquired companies like Recursion before for their technology (e.g., Roche’s acquisition of Flatiron Health for data, or Lilly buying Dynamic Assets for AI). If Recursion’s pipeline starts yielding, an acquisitive pharma might pay a premium. Conversely, Recursion itself might become a consolidator – it could acquire other AI or biotech firms (much like it did with Exscientia). These strategic moves will influence the long-term stock outcome in unpredictable ways.
In summary, the long-term outlook for Recursion (RXRX) ranges from revolutionary success to unfulfilled promise. Optimistically, by 2030 Recursion could stand as a leading “AI Pharma” company, with one or more drugs on the market (or in late-stage trials) and a continuing stream of milestone revenue from partners – in that case, today’s $5 stock price would, in hindsight, look like a bargain. On the pessimistic side, if the AI doesn’t translate to actual cures, Recursion might join the ranks of past biotech “story stocks” that burned through cash without delivering, in which case its stock would significantly underperform or require a buyout rescue.
Given current information, a reasonable long-term expectation is that Recursion will show incremental progress: perhaps a first Phase 3 by ~2027 and a gradual validation of its platform. This would likely support a stock price in the high-single to low-double digits in a few years (assuming moderate dilution), rewarding patient investors but not without volatility. Essentially, Recursion is a long horizon moonshot – it could reshape drug discovery and richly reward stakeholders, but it will require time, execution, and a bit of luck with biology. As one analyst put it, Recursion offers a “compelling narrative” and unique approach, but “the inherent risks… necessitate a cautious and informed investment strategy.” [154] Long-term investors should buckle up for a complex ride, keeping an eye on pipeline readouts and partner momentum as signposts on the journey.
Comparison with Other AI-Focused Biotech Companies
Recursion Pharmaceuticals is often compared to a new breed of biotechnology companies at the intersection of AI and drug development. How does Recursion stack up against its peers, and who are those peers?
- Schrödinger, Inc. (SDGR): Schrödinger is a prominent public company using computational physics and machine learning to design molecules (it has a successful software business and some co-developed drug programs). Both Recursion and Schrödinger are pioneering AI in drug discovery, but their approaches differ. Recursion emphasizes phenomics and big data – generating experimental cellular images at scale – whereas Schrödinger focuses on in silico physics simulations for molecular docking and property prediction. Financially, Schrödinger generates revenue from software licenses (~$100 M/year) which Recursion doesn’t, so Schrödinger has a bit more near-term revenue (though also not profitable). In terms of pipeline, Schrödinger has a couple of partnered compounds in clinical trials (one with Bristol-Myers Squibb in Phase 2), but likewise no approved drugs yet. Both companies have similar market caps in the low-single-digit billions and both have attracted Cathie Wood’s ARK as investors. A Zacks Investment Research comparison in 2025 highlighted that Recursion and Schrödinger “leverage their respective AI platforms” to find novel therapeutics, and investors debate “which has more upside.” [155] Schrödinger might be seen as slightly further along commercially (due to its software sales), while Recursion has arguably larger partnerships and its own experimental pipeline. Some analysts favor Schrödinger for its diversified model, others favor Recursion for its end-to-end vertically integrated platform. It’s quite possible both could succeed (or struggle) in parallel, as they are tackling different slices of the drug discovery puzzle.
- Exscientia: Exscientia was one of Recursion’s closest competitors until Recursion merged with Exscientia in late 2024 in a $5.5 B deal [156]. This merger combined two leaders – Recursion’s strength in phenomics and automation with Exscientia’s prowess in AI-driven precision drug design (e.g., Exscientia designed drug candidates in oncology and immunology in partnership with firms like Sanofi and BMS). Now as one company, Recursion has essentially absorbed Exscientia’s pipeline and partnerships (like the Sanofi deal, Merck KGaA deal, etc. discussed above). The combination created a “vertically-integrated, technology-enabled drug discovery” player with a broad pipeline and ~$850 M cash at merger time [157] [158]. Comparing Recursion post-merger to others, one could say Recursion is the 800-pound gorilla in AI drug discovery now – in terms of headcount (~800 employees) and breadth. The merger also removed a competitor from the landscape, potentially giving Recursion a clearer field.
- BenevolentAI and Others: In Europe, BenevolentAI (listed on Euronext Amsterdam) is another AI drug discovery firm, known for its knowledge graph approach to finding drug targets. It has had collaborations with AstraZeneca. However, BenevolentAI recently faced setbacks and had to restructure in 2023, and its market cap has dwindled. Recursion, by contrast, has remained better capitalized and arguably ahead in execution. Other players include Insilico Medicine (private, based in Hong Kong/US), which has advanced an AI-designed fibrosis drug to Phase II and has partnerships with Fosun and others; Valo Health (US, private) which attempted a SPAC and focuses on an AI platform for cardiovascular and CNS drugs; Atomwise (private, small-molecule AI screening); BioXcel Therapeutics (BTAI, public) which uses AI for drug repurposing and actually has an approved drug for agitation (though its stock has struggled); and big tech companies’ initiatives (e.g., Alphabet’s DeepMind and Isomorphic Labs, Microsoft’s investments in biotech AI).
Compared to most of these, Recursion stands out for the scale of its data generation and its willingness to take drugs all the way through clinical trials (many peers focus on discovery and then out-license). Recursion’s massive compute via Nvidia and its willingness to merge/acquire others (like Exscientia, Cyclica, Valence) also set it apart as a consolidator in this space.
- Traditional Biotech vs TechBio: It’s also useful to compare Recursion to traditional biotech companies of similar stage. A conventional biotech with a handful of Phase 1/2 assets and no revenue might normally be valued much lower (perhaps a few hundred million). Recursion’s ~$2+ B valuation is thus a premium for its tech platform and partnerships. Critics might say Recursion is valued like a tech company without tech-like margins; supporters say it deserves it for potentially revolutionizing R&D. The truth likely lies in the middle – Recursion will need to eventually show that its approach improves the odds or speed of drug development relative to peers. If it does, it could render some traditional approaches obsolete, giving it a major edge. If it doesn’t, then traditional biopharma will remain skeptical and Recursion could be viewed as an overhyped experiment.
- Big Pharma Integration: Another comparison is between Recursion and the internal AI efforts of big pharmaceutical companies. Virtually every large pharma now has an AI partnership or program. For instance, Pfizer works with IBM’s Watson, Roche has its own Institute of Human Biology plus the Recursion deal, and as mentioned, Lilly is building an AI supercomputer with Nvidia to rival Recursion’s [159]. The difference is that Recursion’s DNA is digital from the ground up – it’s arguably more nimble in deploying AI than a 100-year-old pharma trying to retrofit AI into its processes. However, big pharmas have far more resources and data (in clinical trials, etc.) that could eventually surpass what Recursion has. This dynamic will be fascinating to watch: Recursion wants to become the go-to AI platform for pharma (some call it a potential “AWS of biotech”), but pharma might just develop or buy their own solutions if Recursion doesn’t deliver fast enough. For now, the pharma world seems content to partner with specialist companies like Recursion rather than reinvent the wheel internally – a good sign for Recursion’s business model.
In conclusion, Recursion is among the leaders of the AI-driven biotech pack, if not the leader post-Exscientia merger. It compares favorably to peers in terms of partnerships, data scale, and funding. But it shares with all of them the central challenge: converting AI “disruptive potential” into actual drugs on the market. The next few years will likely determine the pecking order in this emerging industry. If Recursion’s bold approach works, it could outpace peers and maybe even become an acquisition target for a major pharma wanting dominance in AI. If it hits roadblocks, investors might rotate to other AI drug startups with different strategies. For now, Recursion is a front-runner in a race that’s just beginning – a race whose prize is nothing less than a new paradigm for how medicines are discovered.
Sources: Recursion Q3 2025 Business Update [160] [161]; CEO transition announcement [162]; Reuters and GlobeNewswire releases [163] [164]; Finimize analysis [165] [166]; Motley Fool & NAI500 commentary [167] [168]; Reuters (NVIDIA deal) [169] [170]; DirectorsTalk & analyst insights [171] [172].
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