Guardant Health stock jumps 7% as Evercore downgrades — what investors watch next

Guardant Health stock jumps 7% as Evercore downgrades — what investors watch next

New York, January 6, 2026, 13:39 EST — Regular session

Guardant Health Inc shares rose 7.2% to $109.24 in afternoon trade on Tuesday, even after Evercore ISI analyst Vijay Kumar cut the stock to “In Line” from “Outperform” while lifting his price target to $105 from $90. The stock traded between $101.02 and $112.12 earlier in the session. Tipranks

The move keeps Guardant near its 52-week high of $112.43 after a steep run that has left the Nasdaq-listed cancer diagnostics firm up about 200% over the past year, according to Investing.com data. Shares have ranged between $34.55 and $112.43 over the last 52 weeks. Investing

Evercore’s downgrade came in a wider “look-ahead” note on medtech and life science tools, where Kumar also downgraded Exact Sciences and other names. He wrote that “recovering end markets and sector rotation” have “set the stage for a 2026 Tools play,” while warning that potential changes to the Affordable Care Act and Medicare “have bears watching.” Tipranks

A Form 4 filing on Monday showed Chief People Officer Terilyn J. Monroe received 17,555 shares through the vesting of restricted stock units, with 7,524 shares withheld by the company to cover taxes at $102.14 per share. Form 4 filings disclose insider transactions to the U.S. Securities and Exchange Commission. Sec

Investors are also watching how reimbursement shapes demand for Shield, Guardant’s blood test for colorectal cancer screening. The company has said the test’s Medicare payment rate for 2026–2027 is set through the Advanced Diagnostic Laboratory Test (ADLT) process — a program that uses private-payer data to help determine Medicare pricing — and co-CEO AmirAli Talasaz has said the designation “reinforces the value that our Shield blood test for colorectal cancer screening brings to patients.” Guardanthealth

Other cancer-testing names were mixed on Tuesday. Natera shares were up about 3.3%, Exact Sciences was little changed, and Illumina rose about 1.9%.

But the rally leaves less room for disappointment. A slower pace of test adoption, pricing pressure, or any shift in reimbursement rules could weigh on expectations for 2026 as blood-based screening and cancer monitoring markets draw more competition.

Stock Market Today

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    January 8, 2026, 9:00 AM EST. AI remains a market catalyst into 2026, with Wall Street projecting S&P 500 earnings to rise about 15.5% next year, up from 13.2% in 2025. The article highlights two AI names, led by CoreWeave, an AI infrastructure provider whose March 2025 IPO sparked a rally as hyperscalers and AI players bought data-center capacity. CoreWeave runs data centers built around GPUs, renting compute power and storage for training and deploying models in the cloud. Its third-quarter 2025 backlog (contracts signed but not yet fulfilled) jumped 271% YoY to $55.6 billion, outpacing a 134% rise in revenue, signaling demand for AI infra. The stock has fallen about 61% from its 52-week high amid concerns about valuations and capital intensity. Analysts say AI should keep fueling gains in 2026; a second AI name is also discussed.
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