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NASDAQ:RARE 30 December 2025 - 31 December 2025

Ultragenyx stock today: RARE steadies premarket after setrusumab Phase 3 miss, FDA gene-therapy filing in focus

Ultragenyx stock today: RARE steadies premarket after setrusumab Phase 3 miss, FDA gene-therapy filing in focus

Ultragenyx shares slipped 0.2% to $22.74 premarket Wednesday after plunging 43.5% Monday on failed Phase 3 trial results for setrusumab in osteogenesis imperfecta. The company said it will cut expenses and shift focus to its DTX401 gene therapy, for which it completed a rolling FDA application. Senior VP Theodore Huizenga sold 85 shares on Dec. 29 to cover taxes. Investors await further details on cost reductions and regulatory milestones.
31 December 2025
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Stock Market Today

  • Friday Options Surge in CrowdStrike, Mosaic, and Vertex Pharmaceuticals
    March 20, 2026, 2:56 PM EDT. Notable options trading volumes were recorded Friday for CrowdStrike Holdings Inc (CRWD), Mosaic Co (MOS), and Vertex Pharmaceuticals (VRTX), all S&P 500 components. CRWD saw 30,610 contracts trade, about 58.6% of its average daily share volume, with $410 strike put options expiring March 2026 leading volume. MOS options reached 64,293 contracts, 56.7% of its typical daily share volume, dominated by $35 strike call options expiring January 2027. VRTX options totaled 7,328 contracts, representing 52.6% of its average daily volume, primarily in $435 strike put options expiring March 2026. These figures highlight significant investor activity in these options markets relative to daily trading averages.
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