December 26, 2025 — GSK plc stock is closing out the year with a familiar mix of “defensive pharma stability” and “pipeline-driven volatility.” The past two weeks delivered a cluster of headline-worthy updates: a U.S. FDA approval for GSK’s twice-yearly asthma biologic, a high-profile U.S. drug-pricing agreement that directly touches GSK’s respiratory franchise, regulatory momentum for expanded vaccine use in Europe, and fresh competitive noise around Shingrix—one of GSK’s biggest profit engines. This is a stock that rarely moves on vibes alone. For GSK shares, regulatory decisions, pricing frameworks, and evidence that new products can offset looming patent expiries are