Mereo BioPharma stock crashes 88% after Phase 3 setrusumab miss sinks brittle-bone hopes
Mereo BioPharma shares plunged 87.65% to $0.29 after late-stage trials of setrusumab failed to meet the main fracture-rate goal in osteogenesis imperfecta. Both Phase 3 studies missed the primary endpoint, though bone mineral density improved and no new safety issues appeared. Analysts cut ratings as the company moved to reduce spending. Trading volume reached about 241 million shares.
