Today: 20 March 2026
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NASDAQ:DNLI 10 December 2025 - 29 January 2026

Denali Therapeutics stock price rises as FDA freezes rival Regenxbio’s Hunter syndrome gene therapy trials

Denali Therapeutics stock price rises as FDA freezes rival Regenxbio’s Hunter syndrome gene therapy trials

Denali Therapeutics shares rose 3.7% to $21.62 Thursday after the FDA halted Regenxbio’s gene therapy trials over a brain tumor case, intensifying focus on Denali’s Hunter syndrome drug under FDA review. Investors await Denali’s clinical data update in early February and a regulatory decision by April 5. The iShares Nasdaq Biotechnology ETF was little changed.
US Stock Market Top Losers Today (December 10, 2025): Polestar, AeroVironment, Denali, Uber and AutoZone Tumble After the Bell

US Stock Market Top Losers Today (December 10, 2025): Polestar, AeroVironment, Denali, Uber and AutoZone Tumble After the Bell

Polestar Automotive shares dropped 25.1% Wednesday after a 1-for-30 reverse stock split and trading halt, with analysts citing ongoing losses and debt concerns. The S&P 500 and Dow hit new highs following a Fed rate cut, but several high-profile stocks, including AeroVironment and Denali Therapeutics, also posted double-digit declines. Microcaps like Work Medical Technology plunged over 85%.
Top Pre‑Market Losers Today (December 10, 2025): AFJK, CBRL, DNLI & AEG Lead Early Declines Before the Bell

Top Pre‑Market Losers Today (December 10, 2025): AFJK, CBRL, DNLI & AEG Lead Early Declines Before the Bell

Aimei Health Technology plunged nearly 50% in pre-market trading after extending its business-combination deadline. Lion Group Holding and JX Luxventure Group each dropped over 35%. Broader U.S. stock futures showed little movement as investors awaited the Federal Reserve’s rate decision later today. Cracker Barrel and Denali Therapeutics also traded lower on fresh news and analyst calls.

Stock Market Today

  • Asia Markets Fall as Iran Conflict Drives Global Risk-Off; Energy Prices Surge
    March 19, 2026, 9:39 PM EDT. Asian markets edged lower following Wall Street losses amid escalating tensions in the Middle East sparked by Iran's attacks on key energy infrastructure. Tehran's strike on Qatar's largest gas plant slashed LNG export capacity by 17% for years, pushing energy prices higher. U.S. natural gas and Brent crude rose over 1%, with gasoline nearing a four-year peak, underscoring supply concerns. Metals saw volatile moves, gold and silver dropping before recovering. Despite market jitters, U.S. President Trump and Israeli Prime Minister Netanyahu signaled restraint, dampening fears of prolonged conflict. A coalition of U.S.-aligned nations pledged to protect key shipping routes, including the Strait of Hormuz. Asian markets showed mixed reactions, with South Korea's Kospi rising, while Australia's S&P/ASX 200 and Hong Kong futures declined. Wall Street indexes closed down modestly after the Federal Reserve held interest rates steady.
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