Today: 20 March 2026
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NASDAQ:PTGX 10 October 2025 - 11 October 2025

Protagonist Therapeutics: Small Biotech Skyrockets on Buyout Buzz & Breakthrough Trials

Protagonist Therapeutics: Small Biotech Skyrockets on Buyout Buzz & Breakthrough Trials

Protagonist Therapeutics shares surged over 30% to nearly $89 on October 10, 2025, after reports that Johnson & Johnson is in talks to acquire the company. Trading was briefly halted due to volatility. The company, valued at about $5.4 billion, recently announced positive trial results for its lead drugs and secured major partnerships with J&J and Takeda.
Protagonist Therapeutics (PTGX) Skyrockets on J&J Buyout Buzz Amid Clinical Breakthroughs

Protagonist Therapeutics (PTGX) Skyrockets on J&J Buyout Buzz Amid Clinical Breakthroughs

Protagonist Therapeutics shares surged over 30% to $89.19 on Oct. 10, 2025, after reports that Johnson & Johnson is in talks to acquire the company. Trading was briefly halted due to volatility. The jump follows positive Phase 2b results for Icotrokinra in ulcerative colitis and recent FDA Breakthrough Therapy Designation for Rusfertide in polycythemia vera.

Stock Market Today

  • Friday Option Activity Highlights OKE, FIX, HCA With Significant Volume
    March 20, 2026, 2:55 PM EDT. Notable options activity was observed on Friday in three S&P 500 stocks: ONEOK Inc (OKE), Comfort Systems USA Inc (FIX), and HCA Healthcare Inc (HCA). OKE saw 23,974 contracts traded, about 47.3% of its average daily volume, driven by high volumes in its $90 call expiring March 2026. FIX recorded 2,013 contracts, 43.4% of average daily shares, largely in the $1260 put expiring April 2026. HCA had 4,644 contracts, representing 41.1% of its daily average, with the $525 put expiring September 2026 seeing the most trades. These volumes suggest increased investor interest in specific strike prices for these stocks over the coming years.
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