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NASDAQ:RZLT 11 December 2025 - 24 December 2025

Rezolute, Inc. (RZLT) Stock News and Forecasts on Dec. 24, 2025: Phase 3 sunRIZE Miss, Analyst Target Cuts, and What Comes Next

Rezolute, Inc. (RZLT) Stock News and Forecasts on Dec. 24, 2025: Phase 3 sunRIZE Miss, Analyst Target Cuts, and What Comes Next

Rezolute shares remain under pressure after the company’s December 11, 2025, announcement that its pivotal sunRIZE Phase 3 trial for ersodetug in congenital hyperinsulinism failed to meet primary and key secondary endpoints. The stock trades near $2.42, well below pre-trial levels, following analyst downgrades and investor-law-firm probes. Two serious hypersensitivity reactions were reported in the trial.
Rezolute (RZLT) Stock Update Dec. 12, 2025: Phase 3 sunRIZE Miss Sparks Selloff, Analysts Reset Targets, and 2026 Catalysts

Rezolute (RZLT) Stock Update Dec. 12, 2025: Phase 3 sunRIZE Miss Sparks Selloff, Analysts Reset Targets, and 2026 Catalysts

Rezolute shares plunged 87% to around $1.40 on December 12, 2025, after its Phase 3 sunRIZE trial for ersodetug in congenital hyperinsulinism failed to meet primary or key secondary endpoints. The trial enrolled 63 patients; efficacy differences versus placebo were not statistically significant. Two serious hypersensitivity reactions were reported. Rezolute plans to meet with the FDA under Breakthrough Therapy Designation.
12 December 2025
US Stock Market Top Losers Today (December 11, 2025): Oracle’s AI Shock, Rezolute’s 88% Crash and Micro‑Cap Meltdowns

US Stock Market Top Losers Today (December 11, 2025): Oracle’s AI Shock, Rezolute’s 88% Crash and Micro‑Cap Meltdowns

The Dow Jones closed at a record high Thursday, rising about 1.3–1.4%, while the Nasdaq fell 0.3–0.4% as Oracle shares plunged up to 15% after weak earnings and a surprise AI spending warning. Micro-cap stocks saw steep losses, with Oriental Culture Holding dropping nearly 90%. The S&P 500 edged higher by 0.1–0.2%.
Biggest Stock Losers Today in the U.S. Market (December 11, 2025): Oracle’s AI Reality Check, Rezolute’s Trial Disaster and Micro‑Cap Carnage

Biggest Stock Losers Today in the U.S. Market (December 11, 2025): Oracle’s AI Reality Check, Rezolute’s Trial Disaster and Micro‑Cap Carnage

Oracle shares dropped 13% intraday after a revenue miss and surging AI spending, erasing tens of billions in value and pulling the Nasdaq 100 down 0.8%. Small-cap stocks including Rezolute, C3is, and GRI Bio plunged up to 90% on clinical failures and delisting threats. The Dow rose 1.3% to record levels. The S&P 500 slipped 0.1%.
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