Biggest Stock Gainers Today: Biotech Breakouts and IBM–Confluent Deal Lead U.S. Market Movers (December 8, 2025)
U.S. stocks were little changed Monday ahead of the Federal Reserve meeting, with the S&P 500 and Dow down 0.03% and the Nasdaq 100 up 0.07%. Small-cap stocks surged, led by biotech firms on clinical trial results and M&A news. Cemtrex soared 134%, Structure Therapeutics 97%, and Wave Life Sciences 92%. The Russell 2000 rose 0.55% intraday.
