Fifth Third–Brex Deal Puts $5.6B AI-Powered Card Platform at Center of Comerica Merger Fight
As Fifth Third Bank chooses Brex to power its commercial cards, the regional lender faces activist lawsuits and community protests over its planned Comerica acquisition. CINCINNATI / DALLAS / NEW YORK — December 10, 2025 Key Points Fifth Third turns to Brex for AI‑powered commercial cards On December 9, Fifth Third Bank announced a multi‑year partnership with Brex, under which the fintech will power the bank’s commercial card program across its commercial banking franchise. Fifth Third Bank+2Business Wire+2 According to the joint announcement, the deal: Fifth Third CEO and chair Tim Spence framed the move as a strategic bet on