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NASDAQ:ALMS 6 December 2025 - 2 February 2026

Alumis stock jumps 129% after Phase 3 psoriasis data; ALMS hits new 52-week high

Alumis stock jumps 129% after Phase 3 psoriasis data; ALMS hits new 52-week high

Alumis shares surged 129% Tuesday after its psoriasis pill, envudeucitinib, met all main goals in Phase 3 trials. About 65% of patients reached PASI 90 and over 40% achieved complete clearance at week 24. The company reported no new safety concerns and plans to file for FDA approval in the second half of 2026. Traders are watching durability and safety data.
Biggest Stock Gainers Today (December 5, 2025): TGL, SMX, WHLR, DBRG, TORO, PRAX and RBRK Lead a Volatile Session

Biggest Stock Gainers Today (December 5, 2025): TGL, SMX, WHLR, DBRG, TORO, PRAX and RBRK Lead a Volatile Session

Treasure Global (NASDAQ:TGL) surged about 276% on December 5, 2025, after a 1-for-20 reverse stock split and news of an acquisition. SMX (NASDAQ:SMX) jumped 135%, and Wheeler Real Estate Investment Trust (NASDAQ:WHLR) gained 98%. The S&P 500, Nasdaq 100, and Dow all closed higher, but small- and mid-cap stocks saw the largest percentage moves.
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