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NASDAQ:GLMD 17 November 2025

Galmed Pharmaceuticals (GLMD) Soars on New Cancer Drug Combo Data: What Today’s Breakthrough Means for Investors – November 17, 2025

Galmed Pharmaceuticals (GLMD) Soars on New Cancer Drug Combo Data: What Today’s Breakthrough Means for Investors – November 17, 2025

Galmed Pharmaceuticals reported that a triple-drug combination of Aramchol, Stivarga, and metformin sharply increased tumor cell killing in GI cancer models. Shares jumped as much as 38.6% premarket and traded around $1.18 by afternoon, with volume exceeding 41 million shares. The company plans a Phase 1b trial at VCU Massey Comprehensive Cancer Center in early 2026. New U.S. patent applications have been filed for the combination.

Stock Market Today

  • United Utilities and Severn Trent Shares Soar on Ofwat Regulatory Boost
    April 30, 2026, 2:13 PM EDT. United Utilities (UU) saw its share price jump 11% in one day, defying typical utility sector expectations amid an £800m share issuance. This surge comes after Ofwat's regulatory settlement raised water bills and allowed for potential additional spending of £2.5bn, which could further increase UU's asset base growth to 10% per year through 2030. Key institutional investors like Australia's Future Fund and Atlas Infrastructure supported UU's equity raise. The planned spending aims to fund infrastructure around Manchester, potentially raising household bills by £10 each. Meanwhile, Severn Trent's shares rose 7%, driven by hopes for similar regulatory opportunities. Both firms have reached all-time highs, outperforming the FTSE 100, illustrating investor confidence despite sector-wide challenges.

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Indiana Gas Prices Near $5 as Refinery Outage, Iran War Hit Drivers

Indiana Gas Prices Near $5 as Refinery Outage, Iran War Hit Drivers

30 April 2026
Indiana’s average regular gasoline price jumped to $4.417 per gallon Thursday, up 32.5 cents from Wednesday and 72.7 cents from a week ago, according to AAA. Some South Bend and Fort Wayne stations hit $4.99. The spike follows a shutdown at BP’s Whiting refinery and volatile crude prices linked to the Strait of Hormuz. Indiana’s average now exceeds the national average of $4.300.
Carvana Stock Fell Even After Record Sales. The Margin Catch Is Why

Carvana Stock Fell Even After Record Sales. The Margin Catch Is Why

30 April 2026
Carvana shares fell 1.8% to $389.39 Thursday afternoon after the company reported record first-quarter sales and profit but a decline in gross profit per vehicle. Carvana sold 187,393 retail vehicles, up 40%, with revenue rising 52% to $6.43 billion and net income reaching $405 million. Gross profit per retail unit dropped to $6,783 from $6,938 a year earlier. Wall Street analysts raised price targets despite margin pressure.
Cigna’s Obamacare Exit Puts 369,000 Members on the Clock for 2027 Coverage

Cigna’s Obamacare Exit Puts 369,000 Members on the Clock for 2027 Coverage

30 April 2026
Cigna Group will exit the Affordable Care Act individual insurance market after 2026, affecting about 369,000 members in 11 states who must find new coverage for 2027. The announcement came as Cigna reported first-quarter revenue of $68.5 billion and raised its 2026 earnings outlook. CVS Health’s Aetna previously withdrew from the ACA market for 2026, impacting about 1 million enrollees.
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