
Tvardi Therapeutics, Inc. jumped as much as 89% on Tuesday after the STAT3 drug developer reported Phase 1 data for TTI-109, but the harder market signal was volume. About 53.9 million shares changed hands by early afternoon, equal to 5.7 times the 9.38 million shares outstanding listed in its latest quarterly filing.
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Today’s highest-ranked model selections.
The catalysts most likely to move markets.
This is the clearest scheduled U.S.-market price-discovery point today and can transmit weekend news into equity-index futures before Monday's cash session.
The Q2 retail package can move NZD and regional risk sentiment. Spillover to U.S. assets is usually secondary unless the result is unusually large.
The absence of U.S. releases, earnings, IPO pricings and split events leaves fewer scheduled catalysts, increasing the relative importance of weekend headlines and positioning at the futures reopen.