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NASDAQ:ZYME 17 November 2025

Jazz Pharmaceuticals (JAZZ) Soars on Breakthrough Ziihera Phase 3 Results in Gastroesophageal Cancer – Key Updates for 17 November 2025

Jazz Pharmaceuticals (JAZZ) Soars on Breakthrough Ziihera Phase 3 Results in Gastroesophageal Cancer – Key Updates for 17 November 2025

Jazz Pharmaceuticals reported positive Phase 3 results for its cancer drug Ziihera in HER2-positive gastroesophageal adenocarcinoma, showing significant improvements in survival endpoints. Jazz shares surged up to 31% pre-market before settling near $141.07 by early afternoon Monday. Ziihera partner Zymeworks saw pre-market gains as high as 59%. The trial enrolled 914 patients across 30 countries.
17 November 2025
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Zymeworks (ZYME) Soars on Positive Phase 3 Ziihera Data in Gastric Cancer – What Today’s Breakthrough Means for the Stock and Patients

Zymeworks (ZYME) Soars on Positive Phase 3 Ziihera Data in Gastric Cancer – What Today’s Breakthrough Means for the Stock and Patients

Zymeworks reported its Phase 3 HERIZON-GEA-01 trial showed Ziihera (zanidatamab-hrii) combinations outperformed trastuzumab plus chemotherapy in HER2-positive gastroesophageal adenocarcinoma. The triple-combination arm also improved overall survival. Jazz Pharmaceuticals plans to file for FDA approval in the first half of 2026. ZYME shares jumped 30–50% pre-market on the news.
17 November 2025
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Stock Market Today

  • Nifty50 and Sensex End Higher on March 20, 2026; IT, PSU Banks, Metals Lead Gains
    March 20, 2026, 10:02 AM EDT. India's benchmark indices closed higher on March 20, 2026. The BSE Sensex rose 0.44% to 74,533 points, and the NSE Nifty gained 0.49% to 23,114. Strong buying in IT, PSU banks and metal stocks buoyed the market despite fuel price hikes and geopolitical tensions in West Asia. Top gainers included Tech Mahindra (3.30%), Tata Steel (3.29%) and Infosys (2.88%), while Hindalco (-2.55%) and HDFC Bank (-2.23%) led declines. Brent crude oil climbed 1.88% to $110.7 a barrel amid the Israel-Iran conflict. Sector-wise, PSU Bank (+2.19%), IT and metal stocks advanced solidly, but financial services and private banks softened. Market breadth was positive with 2,458 stocks rising, reflecting relief-driven buying amid volatile conditions.
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