Pfizer Stock (PFE) Slides After 2026 Guidance: COVID Sales Drop, Patent Cliff and Analyst Forecasts in Focus
Pfizer shares fell nearly 5% to about $25 in U.S. trading Tuesday after the company issued 2026 guidance with adjusted EPS of $2.80–$3.00, below Wall Street estimates. The stock reversed early gains as investors reacted to lower COVID-19 sales and patent expirations expected to pressure results next year. Trading volume topped 55 million shares by late morning.