Novo Nordisk shares (CPH:NOVO-B; NYSE:NVO) drop 4% after cost-driven profit outpaces forecasts but Wegovy concerns persist

Novo Nordisk shares (CPH:NOVO-B; NYSE:NVO) drop 4% after cost-driven profit outpaces forecasts but Wegovy concerns persist

COPENHAGEN, August 5, 2026, 10:26 CEST — Novo Nordisk (CPH:NOVO-B; NYSE:NVO) saw its stock decline by 4% as the company’s profit, which surpassed estimates due to reduced costs, did not fully address ongoing uncertainties over its Wegovy product.

  • Novo’s B shares traded at DKK 295.10–295.25, falling 4.03%. The Copenhagen exchange remained open.
  • Second-quarter adjusted operating profit surpassed the company-compiled consensus by approximately 16%.
  • Adjusted gross margin declined by 4.5 percentage points, while reduced operating expenses helped sustain profitability.

Novo Nordisk’s stock dropped around 4% on Wednesday, following a 6% decline in its ADRs the previous day. Investors were concerned about the quality of profits, even as the company lifted its outlook.

Stock chart for CPH:NOVO-B

Based on an initial calculation using rounded company numbers, savings in sales and adjusted research expenses totaled DKK 2.68 billion. This amount was higher than the approximate DKK 2.47 billion increase reported in adjusted operating profit.

Gross profit remained unchanged in reported kroner. The adjusted gross margin declined to 78.2% from 82.7%. Management anticipates an increase in research and promotional costs in the second half, which will make achieving similar savings more difficult.

Q2 earnings scorecardQ2 2026Year-on-year change
Adjusted salesDKK 78.49 billionIncrease of 6% in DKK; up 7% CER
Adjusted operating profitDKK 33.39 billionUp 8% in DKK; a rise of 11% CER
Adjusted gross margin78.2%Decrease of 4.5 percentage points
Reported net profitDKK 20.99 billionDown 21%

CER refers to constant exchange rates. Data cited are from Novo’s August 4 release.

Adjusted operating profit exceeded the analyst mean of DKK 28.74 billion by roughly 16%. According to Union Investment portfolio manager Markus Manns, oral Wegovy was “just in line with expectations.” Reuters

Approximate Q2 profit bridge, DKK billion2026Estimated 2025Change
Gross profit61.39About 61.39Roughly unchanged
Sales and distribution costs15.00About 17.44-2.44
Adjusted R&D costs11.46About 11.69-0.23
Adjusted operating profit33.39About 30.92+2.47

Preliminary estimates for 2025 are based on rounded growth rates from reported data. Costs are indicated as positive values.

The bridge indicates that operating leverage was primarily driven by a reduction in expenses rather than improvement in product margin. Gross margin was also negatively affected by approximately DKK 3 billion in manufacturing right-sizing charges.

Full-year 2026 outlookAugust 4May 6
Adjusted revenue growth at CER-6% to 0%-12% to -4%
Adjusted operating profit growth at CER-6% to 0%-12% to -4%
Free cash flowDKK 45–55 billionDKK 36–46 billion
Capital spendingAround DKK 55 billionAround DKK 55 billion

Novo increased its growth outlook for both ranges and lifted its cash-flow estimate.

The revision is based on an increase in projected GLP-1 sales. Novo maintains its outlook for falling U.S. revenue and ongoing growth outside the U.S. Price reductions and less Medicaid coverage continue to be limiting factors.

Wegovy pill sales totaled DKK 3.22 billion, below the anticipated DKK 3.3 billion. Novo reported that prescriptions for the product have now surpassed five million since debut.

Obesity treatment, Q2 2026U.S. businessInternational business
Adjusted revenueDKK 12.82 billionDKK 10.33 billion
Sales increase at CER+4%+37%
Wegovy injection growth at CER-22%+46%
Wegovy tablet revenueDKK 3.141 billionDKK 0.077 billion

Growth in international markets delivered the main volume boost against U.S. pricing challenges.

The division by region was pronounced. U.S. sales of injectable Wegovy declined 22%, but total sales from injectables and pills were up 4%. Overseas, obesity revenue climbed 37%.

Wegovy currently commands roughly 90% of the oral obesity market, Chief Executive Mike Doustdar said. Novo has rolled out the drug in the United States, Britain and the UAE, with Germany anticipated to follow.

Pipeline figures muddled the path to commercial advancement. Novo’s CagriSema achieved 15.2% weight loss, while Eli Lilly and Co reported a 15.8% result with Tirzepatide. CagriSema matched non-inferiority for weight loss, but not for HbA1c lowering.

Morten Gregersen of Formuepleje stated that Novo requires “a strong pipeline” ahead of the semaglutide patent expiration. Doustdar remarked that the company must accelerate research efforts and pursue more “shots at goal.” Reuters

Operating profit declined by 16% at CER following DKK 6.3 billion in pipeline impairments. Novo discontinued monlunabant development. The ziltivekimab ZEUS study did not reach its primary endpoint and could lead to an additional impairment in the third quarter.

Risks: Pressure on U.S. prices, reduced Medicaid coverage, patent expiration, and ongoing pipeline costs. Novo intends to reduce Wegovy’s U.S. list price by roughly 50% to $675 starting January 1, 2027.

The earnings call is scheduled for 13:00 CEST. Investors will assess if margins remain stable as expenditures increase in the second half.

TS2 TECH • EXTENDED COVERAGE

Further analysis

Has Novo Nordisk’s 2026 earnings outlook finally stabilised?
Novo raised adjusted sales and operating-profit guidance to 0% to -6% at constant exchange rates. The prior range was -4% to -12%. Q2 adjusted sales rose 7%, while adjusted operating profit gained 11%. Yet first-half adjusted growth was only 2% for both measures. Contraction remains possible. Novo Nordisk
Can the Wegovy pill offset weaker injectable momentum?
The Wegovy pill produced DKK 3.22 billion in Q2 sales. Analysts expected DKK 3.3 billion. Weekly prescriptions exceeded 265,000 by July 17. More than five million prescriptions have been filled since launch. Novo says the pill holds about 90% of its oral obesity market. Lilly’s marketing push and U.S. discounting now test durability. Novo Nordisk
How damaging are the latest pipeline setbacks?
CagriSema matched tirzepatide on weight loss but missed superiority on blood-sugar control. Ziltivekimab also failed its phase 3 cardiovascular endpoint. Novo booked DKK 6.3 billion of pipeline impairments. That included DKK 4.0 billion for monlunabant. The setbacks increase successor risk before semaglutide patent expiries. Novo Nordisk
Is NVO cheap enough after the earnings selloff?
NVO closed August 4 at $44.28, down 6% after results. That price sits 31% below its $64.16 yearly high. The ADR trades near 14.1 times forward earnings. FactSet’s $49.82 average target implies roughly 13% upside. Its $47.04 median target implies only 6%. Consensus includes 14 buys, 21 holds and two sells. Targets span $30.35 to $69.34. Uncertainty is high. The Wall Street Journal
Which catalysts could move the shares next?
International Wegovy pill launches are the clearest near-term commercial catalyst. The pill launched in the UAE during June and Britain during July. Management plans a German launch soon. Wegovy 7.2 mg rolls across Europe during 2026’s second half. Capital Markets Day runs September 20–21. Q3 results follow November 4. Novo Nordisk

Khadija Saeed is a financial markets reporter at TS2.tech, specializing in stocks, technology and emerging industries. She studied economics and finance at the London School of Economics and previously worked in market research before moving into financial journalism. Her coverage focuses on the companies, innovations and economic trends influencing global investors. Follow Khadija Saeed on Google News.

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