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Biotechnology 17 November 2025 - 4 December 2025

CRISPR Therapeutics Stock (CRSP) in December 2025: Price, Forecast, CASGEVY Growth and Takeover Rumors

CRISPR Therapeutics Stock (CRSP) in December 2025: Price, Forecast, CASGEVY Growth and Takeover Rumors

CRISPR Therapeutics shares surged 8.5% to $56 on December 3, landing mid-range between their 52-week low of $30 and high of $78. The company reported a $106 million Q3 net loss on $0.9 million in revenue but holds $1.9 billion in cash. Takeover rumors persist, though no formal bids have emerged. Wall Street price targets range widely, with consensus in the high-$60s to mid-$70s.
4 December 2025
Capricor Therapeutics (CAPR) Soars After HOPE‑3 Win: Latest News, Analyst Targets and Stock Forecast as of December 4, 2025

Capricor Therapeutics (CAPR) Soars After HOPE‑3 Win: Latest News, Analyst Targets and Stock Forecast as of December 4, 2025

Capricor Therapeutics shares surged over 300% to nearly $30 after Phase 3 data showed its Deramiocel cell therapy slowed upper-limb decline by 54% and preserved 91% of heart function in Duchenne muscular dystrophy patients. The HOPE-3 trial enrolled 106 mostly non-ambulatory boys and young men. Trading was volatile, with the stock flagged as “extremely overbought.”
Bristol-Myers Squibb (BMY) Stock Surges on Cobenfy Trial Twist and AI Milestone: Full Outlook as of December 3, 2025

Bristol-Myers Squibb (BMY) Stock Surges on Cobenfy Trial Twist and AI Milestone: Full Outlook as of December 3, 2025

Bristol-Myers Squibb shares jumped over 6% to $51.32 intraday on December 3, 2025, after the company announced a data review and patient re-enrollment for its ADEPT-2 Alzheimer’s psychosis trial. The stock rally follows strong Q3 results and analyst upgrades, despite ongoing legal risks and looming patent expiries.
Capricor Therapeutics (CAPR) Stock Skyrockets on HOPE‑3 Win: FDA Path, Price Targets and 2026 Outlook

Capricor Therapeutics (CAPR) Stock Skyrockets on HOPE‑3 Win: FDA Path, Price Targets and 2026 Outlook

Capricor Therapeutics shares jumped over 380% Wednesday after reporting positive Phase 3 HOPE-3 trial results for deramiocel in Duchenne muscular dystrophy. The stock opened near $30, up from $6.36, hitting intraday highs around $40 on volume over 40 million shares. The FDA previously rejected deramiocel but will review new data for possible approval in 2026. Capricor ended Q3 with $98.6 million in cash.
Capricor Therapeutics (NASDAQ: CAPR) Soars Over 500% After HOPE‑3 Phase 3 Win: What It Means for the Stock Now

Capricor Therapeutics (NASDAQ: CAPR) Soars Over 500% After HOPE‑3 Phase 3 Win: What It Means for the Stock Now

Capricor Therapeutics shares surged over 500% on December 3, 2025, after its Phase 3 HOPE‑3 trial of Deramiocel in Duchenne muscular dystrophy met all primary and key secondary endpoints. The trial showed a 54% slowing of upper limb decline and 91% preservation of heart function versus placebo. Capricor plans to resubmit its BLA to the FDA, addressing a previous Complete Response Letter. The stock traded around $39–40 intraday, up from $6.36.
Polyrizon Ltd (PLRZ) Stock Soars on Nasal Spray Milestone: Latest News, AI Forecasts and Risk Outlook – December 3, 2025

Polyrizon Ltd (PLRZ) Stock Soars on Nasal Spray Milestone: Latest News, AI Forecasts and Risk Outlook – December 3, 2025

Polyrizon Ltd shares surged 130% on December 2 after announcing a manufacturing upscaling milestone for its PL‑14 nasal allergy blocker. The stock closed at $7.33, up from $3.16, with trading volume near 150 million shares. The Israeli biotech, which has no approved products or revenue, now trades around $6 pre-market. Polyrizon develops intranasal hydrogel sprays and remains in the pre-commercial stage.
Amgen (AMGN) Stock Today: Earnings Momentum, Obesity Breakthroughs and Fresh December 2, 2025 Forecasts

Amgen (AMGN) Stock Today: Earnings Momentum, Obesity Breakthroughs and Fresh December 2, 2025 Forecasts

Amgen shares traded at $338.67 on December 2, 2025, up 0.35% and near 52-week highs after strong Q3 results and a raised 2025 outlook. Several institutional investors disclosed reduced AMGN holdings in Q2 filings. Technical analysts flagged a short-term bullish setup. The company’s obesity and cardiovascular drugs remain key pipeline drivers.
ImmunityBio (IBRX) Stock Soars After Q3 Revenue Explosion – Can the Rally Survive a Going‑Concern Warning?

ImmunityBio (IBRX) Stock Soars After Q3 Revenue Explosion – Can the Rally Survive a Going‑Concern Warning?

ImmunityBio shares surged up to 13% on November 28 after reporting Q3 revenue of $32.1 million, up from $6.1 million a year earlier, driven by Anktiva sales. The company posted a Q3 net loss of $67.3 million and a nine-month cash outflow of $234.6 million. Anktiva is FDA-approved for certain bladder cancer patients in the U.S. and recently gained UK approval. Shares remain down mid-teens for the year.
HKEX (388) Stock Today: Hong Kong Exchanges & Clearing Holds Near HK$415 Ahead of Biotech Futures Launch – 27 November 2025

HKEX (388) Stock Today: Hong Kong Exchanges & Clearing Holds Near HK$415 Ahead of Biotech Futures Launch – 27 November 2025

HKEX shares closed at HK$414.80 on November 27, 2025, up 0.4% amid derivatives expiries and anticipation of Hang Seng Biotech Index futures. The stock traded between HK$410.00 and HK$416.00 on about 1.8 million shares. HKEX is up roughly 40–45% year-on-year, trading in the upper half of its 52-week range. The Hang Seng Index ended at 25,942.5, up 0.06%.
SRPT Stock Today, November 25, 2025: Sarepta Rises on SRP‑1003 Progress While Elevidys Risks Still Loom

SRPT Stock Today, November 25, 2025: Sarepta Rises on SRP‑1003 Progress While Elevidys Risks Still Loom

Sarepta shares closed Monday at $18.90, up 6.9%, after a positive safety update for its experimental RNA therapy SRP‑1003. The company hit an enrollment milestone in its DM1 trial, triggering a $200 million payment to Arrowhead Pharmaceuticals. SRPT stock remains down about 85% year-to-date following setbacks with its gene therapy Elevidys.
Telomir Pharmaceuticals (TELO) Unveils Leukemia Breakthrough and Board Change – Full Investor Update for November 21, 2025

Telomir Pharmaceuticals (TELO) Unveils Leukemia Breakthrough and Board Change – Full Investor Update for November 21, 2025

Telomir Pharmaceuticals (NASDAQ: TELO) reported new preclinical data showing its lead drug Telomir-1 killed HL60 leukemia cells in vitro. Director Dr. Craig Eagle resigned from the board, effective November 14, with no dispute cited. TELO stock jumped 8% pre-market but recently traded at $1.39, down 3% from the prior close. Shares remain down about two-thirds year-to-date.
Shuttle Pharmaceuticals (SHPH) Stock Soars on S‑1 Filing, Fresh Financing and AI Pivot – What Today’s Volatile Rally Means for Investors (21 Nov 2025)

Shuttle Pharmaceuticals (SHPH) Stock Soars on S‑1 Filing, Fresh Financing and AI Pivot – What Today’s Volatile Rally Means for Investors (21 Nov 2025)

Shuttle Pharmaceuticals (NASDAQ: SHPH) jumped over 25% in after-hours and pre-market trading on November 21, 2025, after filing a new S-1 registration statement. The filing registers 625,156 shares tied to a pre-funded warrant held by Alternative Investment Capital Inc., which could control about 47% of shares post-offering. Shuttle will not receive new proceeds, as cash was raised in a prior $2.5 million private placement.
InMed Pharmaceuticals (INM) Soars on Alzheimer’s Breakthrough: INM‑901 Study Sparks 20%+ Stock Rally on November 20, 2025

InMed Pharmaceuticals (INM) Soars on Alzheimer’s Breakthrough: INM‑901 Study Sparks 20%+ Stock Rally on November 20, 2025

InMed Pharmaceuticals shares surged over 20% in after-hours and pre-market trading following new preclinical data for its Alzheimer’s candidate INM-901. The company reported successful large-animal studies showing robust bioavailability and no adverse neurological effects. INM traded in the $1.49–$1.55 range Thursday morning on heavy volume, with market cap estimates between $3–5 million.
Psyence BioMed (NASDAQ: PBM) Jumps as It Secures Pharmaceutical‑Grade Ibogaine Supply for Global Clinical Trials – 20 November 2025

Psyence BioMed (NASDAQ: PBM) Jumps as It Secures Pharmaceutical‑Grade Ibogaine Supply for Global Clinical Trials – 20 November 2025

Psyence BioMed (NASDAQ: PBM) secured a sustainable supply of pharmaceutical-grade ibogaine through PsyLabs, receiving an initial 50 kg shipment of high-potency iboga bark for processing. PBM shares rose 21.5% to $3.39 in pre-market trading Thursday, after being named among top healthcare movers.
Nuvation Bio (NUVB) Stock Soars ~50% Today as B. Riley Starts Coverage With $12 Target – 19 November 2025

Nuvation Bio (NUVB) Stock Soars ~50% Today as B. Riley Starts Coverage With $12 Target – 19 November 2025

Nuvation Bio shares surged about 50% to $7.20 in early afternoon trading Wednesday after B. Riley Securities initiated coverage with a “Buy” rating and $12 price target. The rally followed strong commercial results for lung cancer drug IBTROZI and coincided with management’s presentation at the Jefferies Global Healthcare Conference in London. Trading volume hit tens of millions of shares, lifting the company’s market cap to $2.4 billion.
19 November 2025
Can-Fite BioPharma (CANF) Soars on 9-Year Liver Cancer Survival Breakthrough with Namodenoson – November 18, 2025

Can-Fite BioPharma (CANF) Soars on 9-Year Liver Cancer Survival Breakthrough with Namodenoson – November 18, 2025

Can-Fite BioPharma shares surged over 30% Tuesday after reporting a patient with advanced hepatocellular carcinoma remained cancer-free for nine years on its drug Namodenoson. The company also began enrolling patients in a pivotal Phase III trial for the treatment in Israel, Europe, and the U.S. Namodenoson holds Orphan Drug and Fast Track designations.
Olema Pharmaceuticals (OLMA) Soars Over 200% After Roche Breast Cancer Trial Win — What It Means for Palazestrant and Investors on November 18, 2025

Olema Pharmaceuticals (OLMA) Soars Over 200% After Roche Breast Cancer Trial Win — What It Means for Palazestrant and Investors on November 18, 2025

Olema Pharmaceuticals shares surged as much as 220% in pre-market trading on November 18 after Roche announced a Phase 3 win for its oral SERD giredestrant in early-stage breast cancer. The spike was driven by investor read-through to Olema’s similar drug palazestrant, not new Olema data. Volume hit 13.4 million shares, far above average. Shares later retreated toward the low-$20s during regular trading.
Annovis Bio (ANVS) Soars After New Parkinson’s Biomarker Data Show Buntanetap Halts Cognitive Decline – November 17, 2025

Annovis Bio (ANVS) Soars After New Parkinson’s Biomarker Data Show Buntanetap Halts Cognitive Decline – November 17, 2025

Annovis Bio reported new Phase 3 data showing its drug buntanetap halted cognitive decline in early Parkinson’s patients and improved Alzheimer’s-related biomarkers in a key subgroup with amyloid co-pathology. Shares of ANVS surged following the announcement. The company plans to present full biomarker results at the CTAD 2025 conference in December.
17 November 2025
Applied Therapeutics (APLT) Stock Explodes on Heavy Volume as FDA Scrutiny and Cash Concerns Collide – November 17, 2025

Applied Therapeutics (APLT) Stock Explodes on Heavy Volume as FDA Scrutiny and Cash Concerns Collide – November 17, 2025

Applied Therapeutics shares surged up to 70% on November 17, 2025, with trading volume exceeding 40 million shares after Q3 results showed a narrower net loss but cash fell to $11.9 million. Regulatory uncertainty over its lead drug and ongoing legal issues remain unresolved. Analysts are split on the company’s ability to survive without new funding or a partner.
17 November 2025
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Stock Market Today

  • Foreign Funds Dominate Ownership of Spain's Ibex 35 Stock Market
    June 28, 2026, 6:45 AM EDT. The Spanish stock market is increasingly controlled by foreign investors, with nearly 49% of shares owned by nonresidents as of 2024, rising to over 60% by market capitalization. Key players include investment giants BlackRock, Vanguard, and Norway's sovereign wealth fund. The trend reflects a reduction in household ownership from 35% in 1998 to under 16% today, aligning Spain with other EU markets like the UK and France. Experts note that international ownership brings enhanced corporate governance and market liquidity, though it also presents new challenges. The Ibex 35's revenue is also globally diversified, with 65% generated abroad. This shift highlights the global nature of Spain's equities and the growing role of international capital in its market.

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LIVEMarkets rolling coverageStarted: June 28, 2026, 4:00 AM EDTUpdated: June 28, 2026, 6:55 AM EDT Foreign Funds Dominate Ownership of Spain's Ibex 35 Stock Market June 28, 2026, 6:45 AM EDT. The Spanish stock market is increasingly controlled by foreign investors, with nearly 49% of shares owned by nonresidents as of 2024, rising to over 60% by market capitalization. Key players include investment giants BlackRock, Vanguard, and Norway’s sovereign wealth fund. The trend reflects a reduction in household ownership from 35% in 1998 to under 16% today, aligning Spain with other EU markets like the UK and France. Experts note
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