Today: 11 April 2026
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NASDAQ:ENGN 11 November 2025

enGene (ENGN) soars after detailing 62% 6‑month complete response in pivotal bladder‑cancer trial; BLA still targeted for 2H 2026

enGene (ENGN) soars after detailing 62% 6‑month complete response in pivotal bladder‑cancer trial; BLA still targeted for 2H 2026

enGene Holdings reported a 62% complete response rate at 6 months in its pivotal Phase 2 LEGEND trial of detalimogene voraplasmid for high-risk, BCG-unresponsive NMIBC with CIS. The company enrolled 125 patients, above target. Shares surged as much as 62% pre-market after the update. Safety data showed 42% of patients had treatment-related adverse events, mostly mild.

Stock Market Today

  • Varonis Systems Shares Drop 6.7% Amid Sector-Wide AI Concerns
    April 10, 2026, 11:13 PM EDT. Shares of data security firm Varonis Systems (NASDAQ: VRNS) tumbled 6.7% following a UBS downgrade of ServiceNow, which triggered a broader sell-off in enterprise software stocks. Investors fear "seat compression," where AI-driven automation reduces the number of users needed, threatening per-seat revenue models used by companies like Salesforce and Adobe. Recent advancements by AI-native rivals and startups have intensified these concerns. Varonis's stock, already down 37.2% year-to-date and over 68% below its 52-week high, is notably volatile with 16 major moves exceeding 5% in the past year. The ongoing shift toward AI-managed software tools challenges traditional subscription-based software-as-a-service (SaaS) firms and casts uncertainty on legacy business models.

Latest article

UK Stock Market Today: FTSE 100 Climbs as Traders Eye Fragile Iran Ceasefire

UK Stock Market Today: FTSE 100 Climbs as Traders Eye Fragile Iran Ceasefire

10 April 2026
London’s FTSE 100 rose 0.38% to 10,644.28 late Friday morning as investors awaited U.S.-Iran talks in Pakistan. Brent crude climbed 1% to $96.83 a barrel, while sterling eased but was on track for its biggest weekly gain since January. The FTSE 250 gained 0.79%. Britain’s 10-year gilt yield stood at 4.807%.
US Stock Market Today: CPI, Oil and Iran Truce Set the Tone Before the Open

US Stock Market Today: CPI, Oil and Iran Truce Set the Tone Before the Open

10 April 2026
Dow e-minis slipped 0.15% before Friday’s open, with S&P 500 and Nasdaq 100 futures each down 0.08% as traders awaited March CPI data and watched U.S.-Iran tensions. Economists expect headline CPI to rise 0.9% for March and 3.3% year-on-year. Weekly jobless claims increased to 219,000. Brent crude traded near $97 a barrel, while shipping through the Strait of Hormuz remained well below normal.
Wall Street Feels the Heat (and Thrill): Fed Cuts, Tariffs & Mega-Mergers Set NYSE Buzz

US Stock Market Today: Live Updates 10.04.2026

10 April 2026
LIVEMarkets rolling coverageStarted: April 10, 2026, 12:00 AM EDTUpdated: April 10, 2026, 11:41 PM EDT Varonis Systems Shares Drop 6.7% Amid Sector-Wide AI Concerns April 10, 2026, 11:13 PM EDT. Shares of data security firm Varonis Systems (NASDAQ: VRNS) tumbled 6.7% following a UBS downgrade of ServiceNow, which triggered a broader sell-off in enterprise software stocks. Investors fear "seat compression," where AI-driven automation reduces the number of users needed, threatening per-seat revenue models used by companies like Salesforce and Adobe. Recent advancements by AI-native rivals and startups have intensified these concerns. Varonis's stock, already down 37.2% year-to-date and over 68%
MARA Holdings Stock Rises Even After Target Cut as Bitcoin Miner Leans Harder Into AI

MARA Holdings Stock Rises Even After Target Cut as Bitcoin Miner Leans Harder Into AI

9 April 2026
MARA Holdings shares rose 1.7% to $9.67 Thursday despite Cantor Fitzgerald cutting its price target to $10. The company recently sold 15,133 bitcoin for $1.1 billion and agreed to repurchase $1 billion in convertible notes at a discount. MARA is expanding into AI and cloud infrastructure, but fourth-quarter revenue fell 6% and it posted a $1.7 billion net loss.
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