McKesson stock falls today after 16% earnings surge as traders reassess guidance and spinoff clock (MCK)

Shares of McKesson Corp jumped roughly 16.5% to $957.80 in after-hours trading, following a strong rally earlier Thursday.

McKesson Corporation ended the Christmas Eve session essentially flat, then edged slightly lower in thin after-hours trading—an unsurprising setup for a holiday-shortened day when liquidity typically dries up and price moves can be noisy.

McKesson Corporation ended the week on a steadier footing after an early-week dip, closing Friday at $813.80. The stock is still down roughly 9% from its late-November 52‑week high, but it remains one of healthcare’s stronger large-cap performers in 2025 as investors continue to reward its specialty-drug and oncology momentum, capital returns, and portfolio reshaping narrative. MarketWatch+1

At the close, McKesson shares finished at $805.37, down 2.93% on the day and roughly 10% below their recent 52‑week high near $895, even after a powerful rally through most of the year.Wallstrank+2MarketWatch+2

McKesson Corporation is ending November 2025 almost exactly where most long‑term shareholders like it: near an all‑time high, with earnings rising, guidance moving up and big institutional investors still piling into the stock.