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Pharmaceutical Industry 20 December 2025 - 25 December 2025

Eli Lilly (LLY) Stock After Hours Today (Dec. 25, 2025): Holiday Pause, GLP‑1 Catalysts, and What to Watch Before the Market Opens Dec. 26

Eli Lilly (LLY) Stock After Hours Today (Dec. 25, 2025): Holiday Pause, GLP‑1 Catalysts, and What to Watch Before the Market Opens Dec. 26

Eli Lilly shares closed at $1,076.98 after the early NYSE close on Dec. 24, with after-hours quotes near $1,077–$1,078 in thin holiday trading. U.S. exchanges remained shut Dec. 25 for Christmas. The 52-week range stands at $623.78 to $1,111.99. Trading volume is expected to rise when markets reopen Friday, with attention on GLP-1 policy and competition.
25 December 2025
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Bristol-Myers Squibb (BMY) Stock News, Forecasts and Outlook as of Dec. 25, 2025: Breyanzi FDA Win, Eliquis Medicaid Deal, and 2026 Catalysts

Bristol-Myers Squibb (BMY) Stock News, Forecasts and Outlook as of Dec. 25, 2025: Breyanzi FDA Win, Eliquis Medicaid Deal, and 2026 Catalysts

Bristol-Myers Squibb closed at $54.71 on Dec. 24, 2025, after trading between $54.20 and $54.75, with a 52-week range of $42.52 to $63.33. The company agreed to provide Eliquis free to Medicaid starting in 2026 and will donate over seven tons of Eliquis API to the U.S. government. BMS also announced steep discounts for several drugs and secured three years of tariff relief.
25 December 2025
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Bristol-Myers Squibb (BMY) Stock After Hours on Dec. 24, 2025: Key News, Forecasts, and What to Watch Before the Next Market Open

Bristol-Myers Squibb (BMY) Stock After Hours on Dec. 24, 2025: Key News, Forecasts, and What to Watch Before the Next Market Open

Bristol-Myers Squibb closed at $54.71 on Dec. 24, up 0.79%, with after-hours trading flat at $54.70 amid thin holiday volume. The NYSE session ended early for Christmas Eve. Analysts cited by MarketBeat maintained a “Hold” consensus and average 12-month target near current levels. No major company news moved the stock.
25 December 2025
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Omeros (OMER) Stock Surges After Hours on Dec. 24, 2025 After FDA Approves Yartemlea — What to Know Before the Next Market Open

Omeros (OMER) Stock Surges After Hours on Dec. 24, 2025 After FDA Approves Yartemlea — What to Know Before the Next Market Open

Omeros shares jumped 75% to $15.36 in after-hours trading Wednesday after the FDA approved its first commercial product, YARTEMLEA, for a rare post-transplant complication. The stock saw heavy volume and a wide range, with multiple trading halts reported. U.S. markets closed early for Christmas Eve and will reopen Friday. The FDA had previously rejected the drug in 2021.
24 December 2025
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Merck (MRK) Stock After Hours Today: Shares Hit a New 52-Week High on Dec. 24, 2025 — What to Know Before U.S. Markets Reopen

Merck (MRK) Stock After Hours Today: Shares Hit a New 52-Week High on Dec. 24, 2025 — What to Know Before U.S. Markets Reopen

Merck shares closed near $106.45 on Dec. 24, up 1.3%, hitting a new 52-week high in a shortened Christmas Eve session. The stock contributed to the Dow’s advance as U.S. markets posted record closes. Trading volume remained thin after hours. No new corporate news was released, but investors continued to react to last week’s drug-pricing agreement with the Trump administration.
24 December 2025
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Edgewise Therapeutics Stock (EWTX) Jumps on EDG-7500 CIRRUS-HCM Update: Dec. 24, 2025 News, Analyst Forecasts, and Key Catalysts

Edgewise Therapeutics Stock (EWTX) Jumps on EDG-7500 CIRRUS-HCM Update: Dec. 24, 2025 News, Analyst Forecasts, and Key Catalysts

Edgewise Therapeutics shares jumped 21% to $26.37 intraday Wednesday after the company reported positive interim safety data for its EDG-7500 therapy in hypertrophic cardiomyopathy. The update showed no clinically meaningful LVEF reductions and no LVEF drops below 50% among 20 patients, with one new-onset atrial fibrillation event disclosed. Over 40 participants have enrolled in Part D of the trial.
24 December 2025
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Merck (MRK) Stock After Hours Today (Dec. 23, 2025): Shares Slip Slightly After the Close as Investors Track TrumpRx Pricing Deal, FDA Fast-Track Vouchers, and Fresh Wall Street Targets

Merck (MRK) Stock After Hours Today (Dec. 23, 2025): Shares Slip Slightly After the Close as Investors Track TrumpRx Pricing Deal, FDA Fast-Track Vouchers, and Fresh Wall Street Targets

Merck closed Tuesday at $105.04, up 0.3%, then slipped to about $104.81 in after-hours trading. The stock is trading near its 52-week high of $105.84 after gains tied to new White House drug-pricing agreements and FDA fast-track headlines. Merck will sell several diabetes drugs at roughly 70% off list prices under the TrumpRx plan.
24 December 2025
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Bristol-Myers Squibb (BMY) Stock News Today: Supreme Court Bid, Drug-Pricing Deals, Dividend Boost, and 2026 Forecasts (Dec. 23, 2025)

Bristol-Myers Squibb (BMY) Stock News Today: Supreme Court Bid, Drug-Pricing Deals, Dividend Boost, and 2026 Forecasts (Dec. 23, 2025)

Bristol-Myers Squibb shares traded near $54 midday Tuesday, down about 1%, after the company and Johnson & Johnson asked the U.S. Supreme Court to review challenges to Medicare drug price negotiations. Eliquis, a key Bristol Myers drug, is set for negotiated Medicare pricing starting January 1, 2026. Guggenheim reiterated a Buy rating on BMY despite new competition for its Camzyos therapy.
23 December 2025
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Eli Lilly Stock (LLY) Today: Wegovy Pill Approval Raises the Stakes in GLP‑1s as Wall Street Forecasts Point to a High‑Expectation 2026

Eli Lilly Stock (LLY) Today: Wegovy Pill Approval Raises the Stakes in GLP‑1s as Wall Street Forecasts Point to a High‑Expectation 2026

Eli Lilly shares hovered near record highs Tuesday after the FDA approved Novo Nordisk’s first oral Wegovy pill, intensifying rivalry in the obesity drug market. LLY traded around $1,077 as investors weighed Novo’s launch against Lilly’s own oral candidate, orforglipron, which could reach the market in 2026. Both firms have signaled lower pricing for new pills as competition heats up.
23 December 2025
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GSK Stock News Today (Dec. 23, 2025): Buyback Update, Director Buying, US Drug-Pricing Deal, and FDA Wins — What Analysts Forecast Next

GSK Stock News Today (Dec. 23, 2025): Buyback Update, Director Buying, US Drug-Pricing Deal, and FDA Wins — What Analysts Forecast Next

GSK disclosed a buyback of 232,912 shares on Dec. 19, 2025, at an average price of 1,807.58p, bringing total repurchases since late September to over 14.5 million shares. The company also reported director share purchases and reached a US drug pricing agreement. Shares traded near $48.59 Tuesday, little changed. Samsung Biologics agreed to buy a US facility from GSK for $280 million.
23 December 2025
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Alnylam Pharmaceuticals (ALNY) Stock: Nasdaq-100 Entry, Amvuttra Momentum, Analyst Targets and Key Risks to Know Before the Dec. 22, 2025 Market Open

Alnylam Pharmaceuticals (ALNY) Stock: Nasdaq-100 Entry, Amvuttra Momentum, Analyst Targets and Key Risks to Know Before the Dec. 22, 2025 Market Open

Alnylam Pharmaceuticals joins the Nasdaq-100 before the U.S. market opens Dec. 22, prompting index-tracking funds to adjust positions. Shares last closed at $400.23. The company’s drug Amvuttra recently secured routine NHS use in England and Health Canada approval for ATTR cardiomyopathy. Alnylam also announced a $250 million manufacturing expansion and new FDA recognition for its technology platform.
22 December 2025
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Amicus Therapeutics (FOLD) Stock Week Ahead: $14.50 BioMarin Buyout Puts the Deal Spread—and New Filings—Front and Center (Dec. 22–26, 2025)

Amicus Therapeutics (FOLD) Stock Week Ahead: $14.50 BioMarin Buyout Puts the Deal Spread—and New Filings—Front and Center (Dec. 22–26, 2025)

BioMarin Pharmaceutical agreed Friday to acquire Amicus Therapeutics for $14.50 per share in cash, valuing the company at $4.8 billion. FOLD shares closed near $14.18 after jumping 30% on the news. The deal is expected to close in Q2 2026, pending shareholder and regulatory approvals. Amicus disclosed a $175 million breakup fee and a June 19, 2026 outside date.
22 December 2025
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Amgen (AMGN) Stock Week Ahead Forecast: Drug-Price Deal Fallout, Analyst Targets, and Year-End Catalysts to Watch (Dec. 22–26, 2025)

Amgen (AMGN) Stock Week Ahead Forecast: Drug-Price Deal Fallout, Analyst Targets, and Year-End Catalysts to Watch (Dec. 22–26, 2025)

Amgen shares last traded near $327.38 as investors weighed a new FDA label expansion and U.S. drug-pricing deals announced Dec. 19. The NYSE will close early Dec. 24 and remain shut Dec. 25, thinning liquidity and increasing volatility risk. Amgen, a Dow component, remains sensitive to policy headlines and year-end positioning.
21 December 2025
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Amicus Therapeutics Stock (FOLD) News: BioMarin’s $14.50 Cash Buyout, Deal Timeline, and the Latest Forecasts (Dec. 21, 2025)

Amicus Therapeutics Stock (FOLD) News: BioMarin’s $14.50 Cash Buyout, Deal Timeline, and the Latest Forecasts (Dec. 21, 2025)

BioMarin Pharmaceutical will acquire Amicus Therapeutics for $14.50 per share in cash, valuing the deal at about $4.8 billion. Amicus stock closed at $14.18 on December 19, up 30% in a day and near the offer price. The deal is expected to close in Q2 2026, pending regulatory and shareholder approval. Amicus resolved key Galafold patent litigation ahead of the announcement.
21 December 2025
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Pfizer Stock (PFE) in Focus: 2026 Guidance, Drug-Price Deal Pressures, and Pipeline Catalysts Investors Are Watching

Pfizer Stock (PFE) in Focus: 2026 Guidance, Drug-Price Deal Pressures, and Pipeline Catalysts Investors Are Watching

Pfizer forecast 2026 revenue of $59.5–$62.5 billion and adjusted EPS of $2.80–$3.00, both below Wall Street estimates. The company expects a $1.5 billion drop in COVID product sales and another $1.5 billion hit from patent expirations. Pfizer signed a Medicaid pricing deal with the Trump administration, warning of margin compression. Shares closed at $25.25 on Dec. 19.
21 December 2025
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Vertex Pharmaceuticals (VRTX) Stock News, Forecasts and Analyst Outlook on Dec. 20, 2025: Casgevy Pediatric Data, Kidney Pipeline Momentum, and Journavx Launch Watch

Vertex Pharmaceuticals (VRTX) Stock News, Forecasts and Analyst Outlook on Dec. 20, 2025: Casgevy Pediatric Data, Kidney Pipeline Momentum, and Journavx Launch Watch

Vertex Pharmaceuticals reported new pediatric results for Casgevy on Dec. 6, showing all four children with severe sickle cell disease were free of vaso-occlusive crises for at least 12 months. Twelve pediatric beta thalassemia patients remained transfusion-free for at least a year. Vertex plans global regulatory filings in 2026. One TDT patient died from busulfan-related complications.
21 December 2025
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Gilead Sciences Stock (NASDAQ: GILD) Today: TrumpRx Drug-Pricing Deal, HIV Pipeline Momentum, and Wall Street Forecasts (Dec. 20, 2025)

Gilead Sciences Stock (NASDAQ: GILD) Today: TrumpRx Drug-Pricing Deal, HIV Pipeline Momentum, and Wall Street Forecasts (Dec. 20, 2025)

Gilead Sciences shares closed at $124.29 on Dec. 19, up 2.32%, after President Trump announced a drug pricing deal with nine major firms, including Gilead. The agreement includes Medicaid price cuts, cash-pay discounts via TrumpRx.gov, and a three-year tariff exemption tied to increased U.S. manufacturing. Gilead expects the financial impact to be manageable in 2026.
20 December 2025
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Edgewise Therapeutics (EWTX) Stock: Latest News, Analyst Forecasts, and What’s Driving the December 2025 Surge

Edgewise Therapeutics (EWTX) Stock: Latest News, Analyst Forecasts, and What’s Driving the December 2025 Surge

Edgewise Therapeutics shares surged 20.8% to $25.55 on December 19, 2025, amid heavy trading and technical breakout signals. The move follows recent investor conference appearances and ongoing focus on late-stage neuromuscular and cardiovascular drug programs. As of September 30, the company reported $563.3 million in cash and a Q3 net loss of $40.7 million.
20 December 2025
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Amicus Therapeutics Stock (FOLD) Surges as BioMarin Agrees to Buy the Rare-Disease Biotech for $4.8 Billion

Amicus Therapeutics Stock (FOLD) Surges as BioMarin Agrees to Buy the Rare-Disease Biotech for $4.8 Billion

BioMarin Pharmaceutical agreed to acquire Amicus Therapeutics in an all-cash deal valued at about $4.8 billion, offering $14.50 per share. Amicus stock jumped roughly 30% to $14.18 on heavy volume, trading just below the bid as investors assess deal closure risks. Both boards approved the transaction, with closing targeted for Q2 2026 pending shareholder and regulatory approvals.
20 December 2025
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Stock Market Today

  • Why Investors Should Sell Rapid7 Amid Declining Metrics and Consider Alternatives
    May 21, 2026, 3:54 PM EDT. Rapid7 (RPD) shares have plunged nearly 50% since November 2025, raising concerns among investors. Key red flags include stagnant billings at $199.2 million, indicating customer acquisition struggles amid stiff competition. The firm's customer acquisition cost (CAC) payback period turned negative this quarter, suggesting sales efforts are not recouping expenses efficiently. Additionally, Rapid7's GAAP operating margin shrank by 1.7 percentage points over two years to 1.3%, questioning profitability despite revenue growth. Trading at 0.5× forward price-to-sales, the stock appears cheap but poses significant downside risks given weak fundamentals. Analysts advise caution and suggest considering higher quality alternatives before investing in Rapid7.

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