Zymeworks (ZYME) Soars on Positive Phase 3 Ziihera Data in Gastric Cancer – What Today’s Breakthrough Means for the Stock and Patients

Zymeworks (ZYME) Soars on Positive Phase 3 Ziihera Data in Gastric Cancer – What Today’s Breakthrough Means for the Stock and Patients

What Zymeworks Announced Today Before the U.S. market open on November 17, 2025, Vancouver‑based Zymeworks Inc. (ZYME) released topline Phase 3 data from its pivotal HERIZON‑GEA‑01 study, evaluating Ziihera (zanidatamab‑hrii) in first‑line treatment of HER2‑positive locally advanced or metastatic gastroesophageal adenocarcinoma, a group that includes cancers of the stomach, gastroesophageal junction, and esophagus. GlobeNewswire+1 The trial compared three regimens: According to Zymeworks and its partners Jazz Pharmaceuticals and BeOne Medicines, HERIZON‑GEA‑01 delivered several key findings: GlobeNewswire+2GlobeNewswire+2 On the back of these data, Jazz plans to: GlobeNewswire+1 For Zymeworks, which originally discovered Ziihera using its Azymetric™ bispecific antibody platform, the company
Saudi Stocks Edge Lower as Aramco, Aslak Go Ex‑Dividend; Arabian Drilling Wins SAR 2B+ Renewals — TASI Closes at 11,039 (Nov. 17, 2025)

Saudi Stocks Edge Lower as Aramco, Aslak Go Ex‑Dividend; Arabian Drilling Wins SAR 2B+ Renewals — TASI Closes at 11,039 (Nov. 17, 2025)

Riyadh — Monday, Nov. 17, 2025. Saudi Arabia’s Tadawul All Share Index (TASI) slipped for a second straight session on Monday, easing 0.12% to close at 11,039.36 after trading between 11,105.85 (high) and 11,034.68 (low). The modest drop followed Sunday’s sharper decline and came amid a busy day of corporate headlines and ex‑dividend moves on the Saudi Exchange. Investing.com+1 Market snapshot What moved Saudi stocks today Ex‑dividend pressure (Aramco, Aslak). The exchange confirmed Saudi Aramco (2222) and Aslak (1301) traded ex‑dividend today, a technical factor that typically trims price levels by the dividend amount on the ex‑date and can add
Shenzhen Stock Exchange Today (Nov 17, 2025): Shenzhen Component slips 0.11%; Guanghetong (00638) added to Southbound Stock Connect; ‘Nanwang Digital’ (301638) set to list; ETF and local‑government bonds lined up

Shenzhen Stock Exchange Today (Nov 17, 2025): Shenzhen Component slips 0.11%; Guanghetong (00638) added to Southbound Stock Connect; ‘Nanwang Digital’ (301638) set to list; ETF and local‑government bonds lined up

Shenzhen, China — November 17, 2025. The Shenzhen Stock Exchange (SZSE) eased on Monday as growth stocks underperformed and investors digested a run of exchange notices on Stock Connect eligibility, listings and fresh fixed‑income supply. By the close, the Shenzhen Component Index edged 0.11% lower to 13,202, while the ChiNext growth board slipped 0.2% to 3,105.2. Across Shanghai and Shenzhen, combined cash‑equity turnover totaled 1.91 trillion yuan, with lithium and forestry names firmer but antimony and glass‑fiber counters weaker. News Key developments from SZSE on November 17, 2025 1) Southbound Stock Connect: Guanghetong (00638) added SZSE confirmed that Hong Kong‑listed
Shanghai Stock Exchange Today (Nov 17, 2025): Shanghai Composite slips 0.46% to 3,972 as lithium rally offsets broader risk-off mood

Shanghai Stock Exchange Today (Nov 17, 2025): Shanghai Composite slips 0.46% to 3,972 as lithium rally offsets broader risk-off mood

Key takeaways Market wrap—what moved in Shanghai today Chinese equities eased on Monday, November 17, 2025, as investors locked in recent gains and tracked a softer regional tone. At the close, the Shanghai Composite finished 0.46% lower at 3,972.03, the Shenzhen Component slipped 0.11%, and ChiNext shed 0.20%. Turnover across Shanghai and Shenzhen totaled ¥1.91 trillion, indicating slightly lighter participation than at the end of last week. Xinhua News Why the tape looked heavy Globally, risk appetite cooled with markets eyeing Nvidia’s mid‑week results—a widely watched read‑through for AI‑linked demand—and digesting cross‑currents from geopolitics to policy. That risk‑off undertone bled
Euronext Paris Shocks Markets with Historic Roots, Surging Stocks & Bold 2025 Moves

Euronext Today: CAC 40 slips as luxury names weigh; Euronext launches 2026 bond tender; Athens bourse bid enters final day — 17 November 2025

European equities began the week on the back foot Monday, with Euronext’s major benchmarks edging lower as investors braced for a backlog of U.S. economic releases and the week’s headline corporate result from Nvidia. Financials and luxury houses were among the early drags, while aerospace outperformed. Reuters+1 Market at a glance (Mon, 17 Nov 2025) Data points reflect conditions during the European morning/late morning on 17 Nov 2025 and may be delayed. Reuters What moved Euronext this morning Corporate: Euronext launches tender for 2026 bonds and lines up new issue Euronext N.V. this morning opened an any‑and‑all cash tender for
17 November 2025
Hong Kong Stocks Today (Nov 10, 2025): Hang Seng Jumps 1.6% as China CPI Turns Positive; Pop Mart and CNOOC Lead Gains

HKEX Today: Hang Seng slips 0.7% as CNGR Advanced Material lists; Southbound flows favor Tracker Fund & Alibaba — November 17, 2025

Hong Kong — The Hong Kong Stock Exchange (HKEX) closed lower on Monday, November 17, 2025, as profit‑taking and regional geopolitics cooled risk appetite. The session also featured a closely watched debut by CNGR Advanced Material and a steady drumbeat of microstructure updates from the exchange, while Southbound investors concentrated buy orders in the city’s most‑traded ETFs and big‑cap tech. news.rthk.hk Market at a glance New listing: CNGR Advanced Material (2579) prices at HK$34, begins trading Battery materials group CNGR Advanced Material Co., Ltd. (2579)priced its Hong Kong H‑share IPO at HK$34.00 per share and commenced trading today on HKEX’s
Dalal Street in Turmoil: Sensex Plunges 2,500 Points in a Week – Should You Buy the Dip or Brace for More?

BSE Sensex Today, 17 November 2025: Sixth Straight Gain as RBI Export Relief, Bihar Verdict and Retail Flows Lift Dalal Street

Indian equities on the Bombay Stock Exchange (BSE) closed firmly higher on Monday, 17 November 2025, extending their winning streak to a sixth straight session as financials, autos and select midcaps drew strong buying interest. The rally unfolded against a backdrop of fresh Reserve Bank of India (RBI) relief for tariff‑hit exporters, political stability after the Bihar election verdict, and sustained retail investor interest in BSE itself. The Economic Times+3The Economic Times+3Business Today+3 Headline Numbers: Sensex and Nifty Reclaim Momentum At the close, the S&P BSE Sensex ended around 84,950, up about 388 points or 0.46%, while the Nifty 50
Stock Market Today: Nifty 50 Closes Above 26,000 on NSE, Bank Nifty Hits Record High – Full Round‑Up for 17 November 2025

Stock Market Today: Nifty 50 Closes Above 26,000 on NSE, Bank Nifty Hits Record High – Full Round‑Up for 17 November 2025

Mumbai, 17 November 2025 – The National Stock Exchange of India (NSE) kicked off the new trading week on a strong note as benchmark indices extended their winning streak to a sixth consecutive session. The Nifty 50 reclaimed and closed above the psychologically important 26,000 mark, while the Bank Nifty scaled a fresh record high, underscoring broad-based optimism across Indian equities. Business Standard+2Moneycontrol+2 Headline indices on NSE: Nifty 50 above 26,000, Sensex near 85,000 On the NSE, the Nifty 50 ended the day at 26,013.45, up 103.4 points (0.40%), marking the index’s first close above 26,000 since late October and
Inside Deutsche Börse & Frankfurt Stock Exchange: Europe’s Financial Powerhouse Unveiled (2025 Update)

Deutsche Börse Today – DAX Stays Below 24,000 as New Rules, Buyback and ECB Warnings Shape Frankfurt (17 November 2025)

The German blue‑chip index DAX and the Frankfurt Stock Exchange started the new week on a cautious note. While trading opened with small gains, the market quickly slipped back under the psychologically important 24,000‑point mark as investors weighed fresh regulatory changes at Deutsche Börse, an ongoing share buyback, and renewed warnings from the European Central Bank (ECB) about elevated financial‑market risks. MarketScreener+2Deutsche Börse Group+2 DAX on 17 November 2025: Nervous but orderly trading in Frankfurt At the opening bell in Frankfurt, the DAX edged up around 0.14% to roughly 23,910 points, staying just under the 24,000 threshold that has acted
17 November 2025
TSX Today: Toronto Stock Exchange Steadies Ahead of Key Inflation Data (November 17, 2025)

TSX Today: Toronto Stock Exchange Steadies Ahead of Key Inflation Data (November 17, 2025)

Canada’s main stock market is starting the week in a holding pattern, with investors laser‑focused on fresh inflation numbers that could shape the Bank of Canada’s next move and set the tone for the S&P/TSX Composite Index into year‑end. Early look: Futures point to a flat open Futures tied to the S&P/TSX Composite Index were essentially unchanged early Monday, with December contracts down about 0.03% as of 5:50 a.m. ET, signalling a cautious open for the Toronto Stock Exchange on November 17, 2025. Reuters The muted move comes after a volatile stretch: That backdrop sets up today as a classic
Tokyo Stock Exchange Surges to Record Highs on AI Boom – Inside the Nov 3, 2025 Rally

Tokyo Stock Exchange Today: Nikkei 225 Slips as GDP Shock and China Travel Spat Batter Tourism Stocks – 17 November 2025

Tokyo’s stock market ended Monday slightly lower, capping a volatile session in which geopolitical tensions with China and weaker‑than‑expected economic data overshadowed a tentative rebound in global risk appetite. The Nikkei 225 closed at 50,323.91, down 52.62 points or 0.10%, while the broader TOPIX fell 0.37% to 3,347.53.Nikkei Indexes+1 Key Takeaways for Tokyo Stock Exchange on 17 November 2025 Tokyo Stock Market Overview: Modest Losses After a Wild Intraday Swing Despite the modest closing move, Monday’s session on the Tokyo Stock Exchange (TSE) was anything but calm. Market breadth underlined the cautious mood: Regionally, Tokyo’s performance lagged some peers but
Most Americans Still Want to Retire at 63 — But New Social Security and 401(k) Rules Show Why That’s a Risky Move

Most Americans Still Want to Retire at 63 — But New Social Security and 401(k) Rules Show Why That’s a Risky Move

On November 17, 2025, the traditional picture of retirement in America is colliding with some hard new numbers. A recent analysis of the 2024 MassMutual Retirement Happiness Study found that retirees and pre‑retirees see 63 as the “perfect” age to leave work. The average retirement age today is about 62, right in that early‑60s window.Moneywise But zoom out to the latest Social Security changes, 2026 retirement contribution limits, and fresh warnings about the program’s finances, and a different story emerges: retiring at 63 is often financially fragile, not ideal. Below is a breakdown of what the new data and today’s

Stock Market Today

Macquarie Group share price slips 2% after APRA eases liquidity curbs — what to watch next week

Macquarie Group share price slips 2% after APRA eases liquidity curbs — what to watch next week

7 February 2026
Macquarie Group shares fell 2.17% to A$207.83 Friday, marking a third straight decline as the ASX 200 slid 2%. Australia’s regulator trimmed liquidity requirements for Macquarie Bank after improvements in controls. Macquarie Asset Management announced two UK utility deals, including full ownership of Last Mile Infrastructure and the purchase of Energy Assets Group. Investors await Tuesday’s operational briefing.
Wall Street Feels the Heat (and Thrill): Fed Cuts, Tariffs & Mega-Mergers Set NYSE Buzz

Stock Market Today 07.02.2026

7 February 2026
LIVEMarkets rolling coverageStarted: February 7, 2026, 12:00 AM ESTUpdated: February 7, 2026, 1:05 AM EST Crude Oil Prices Rise on Dollar Weakness, Geopolitical Tensions February 7, 2026, 12:52 AM EST. Crude oil prices edged higher on Friday, supported by a weaker U.S. dollar and escalating geopolitical risks in the Middle East. March WTI crude gained 0.41%, rebounding from early losses, while gasoline prices rose 1.38%. Doubts over a U.S.-Iran nuclear deal loom after reports of Iran's refusal to halt uranium enrichment, raising the risk of military action and potential disruption of vital shipping routes. Additionally, a surge in U.S. consumer
Seagate (STX) stock jumps nearly 6% as Citi hikes target — what to watch next week

Seagate (STX) stock jumps nearly 6% as Citi hikes target — what to watch next week

7 February 2026
Seagate shares rose 5.9% to $429.32 Friday after Citigroup raised its price target to $480 and reiterated a buy rating. The gain ended a two-day slide but left the stock 6.6% below its Feb. 3 high. CEO Dave Mosley sold 20,000 shares on Feb. 2 under a pre-arranged plan, SEC filings show. U.S. jobs and inflation data next week are seen as key tests for tech stocks.
Cummins (CMI) stock price rebounds after earnings whipsaw as investors eye data-center power demand

Cummins (CMI) stock price rebounds after earnings whipsaw as investors eye data-center power demand

7 February 2026
Cummins shares jumped 6.8% to $577.73 Friday, recovering from a nearly 9% post-earnings drop the day before. The company reported Q4 revenue up 1% to $8.54 billion, took a $218 million charge tied to its hydrogen business, and guided for 2026 EBITDA of 17–18% of sales. Demand for data center generators offset weakness in North American truck markets. Analyst reaction was mixed; Truist raised its price target.
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