Spyre Therapeutics stock slid 6.6% into the weekend — here’s what matters before Monday’s open
NEW YORK, Jan 4, 2026, 11:15 ET — Market closed Spyre Therapeutics shares fell 6.6% to $30.58 on Friday, then ticked up about 2% in after-hours trading, as U.S. markets headed into the weekend. Yahoo Finance With markets shut on Sunday, the Friday move leaves Spyre starting the new week with momentum tilted lower — a reminder that development-stage biotech stocks can swing sharply even without fresh headlines. That matters now because Spyre’s valuation hinges on clinical data due in 2026, not product sales. Any shift in expectations for timing or quality of those readouts can drive outsized moves. In