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NASDAQ:CNTA 11 December 2025

Centessa Pharmaceuticals (CNTA) Stock on December 11, 2025: CEO Shake‑Up, Analyst Upgrades and 2026 Orexin Catalysts

Centessa Pharmaceuticals (CNTA) Stock on December 11, 2025: CEO Shake‑Up, Analyst Upgrades and 2026 Orexin Catalysts

Centessa Pharmaceuticals announced Mario Alberto Accardi will become CEO on January 1, 2026, as the company’s orexin drug program nears pivotal studies. Shares fell 8.4% to about $27 after the news. Current CEO Saurabh Saha will move to an advisory role. The company’s lead candidate, ORX750, is set for registrational trials in early 2026.

Stock Market Today

  • FTSE 100 Drops Marginally as Miners Weigh; UK Private Sector Contracts Again
    June 23, 2026, 12:37 PM EDT. The FTSE 100 edged down 0.1% to 10,428.85, dragged by weaker mining stocks amid UK's private sector contraction for a second month in June. The FTSE 250 fell 1.2%, and AIM All-Share dropped 1.5%. The S&P Global UK composite output index missed expectations at 49.4, signaling ongoing economic softness, especially in services. The pound weakened against the dollar but strengthened slightly versus the euro. US markets saw significant tech declines with Nasdaq down 2%, led by plunges in Micron (-11%), AMD (-5.9%), and Nvidia (-3.8%), reflecting investor concerns over the sustainability of AI-driven investment growth. Asian markets followed suit with notable tech sell-offs. Micron's upcoming earnings report is viewed as a key indicator for the AI capital expenditure outlook.

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