Today: 22 March 2026
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NASDAQ:CRNX 26 September 2025 - 7 January 2026

Crinetics Pharmaceuticals (CRNX) Stock Drops After CMO Departure Filing: Latest News, Analyst Forecasts, and What’s Next (Dec. 18, 2025)

Crinetics Pharmaceuticals (CRNX) Stock Drops After CMO Departure Filing: Latest News, Analyst Forecasts, and What’s Next (Dec. 18, 2025)

Crinetics Pharmaceuticals shares fell about 8% Thursday after a regulatory filing disclosed Chief Medical and Development Officer Dr. Dana Pizzuti will step down December 31. She will transition to a Strategic Regulatory and Development Advisor role in early 2026. The stock traded in the low-to-high $40s as investors reacted to the leadership change.
18 December 2025
Massive Moves: Record Deals, FDA Wins & Crypto Mania Propel Top Stock Gainers (Sep 29, 2025)

Massive Moves: Record Deals, FDA Wins & Crypto Mania Propel Top Stock Gainers (Sep 29, 2025)

Electronic Arts shares jumped 15% after agreeing to a $55 billion buyout led by Saudi Arabia’s PIF, offering $210 per share. Crinetics Pharmaceuticals soared 28% as the FDA approved its oral acromegaly drug. QMMM Holdings surged 19% before the SEC halted trading over suspected manipulation. Scholar Rock gained 12% despite an FDA delay for its spinal atrophy drug.
Crinetics (CRNX) Stock Skyrockets on FDA Approval – Full 2025 Investor Update

Crinetics (CRNX) Stock Skyrockets on FDA Approval – Full 2025 Investor Update

Crinetics Pharmaceuticals shares surged 28% to around $46 on Sept. 26 after the FDA approved its first drug, Palsonify, for acromegaly. Trading volume spiked nearly tenfold amid heavy short-covering. The company plans to launch Palsonify in October at a $290,000 annual list price. Crinetics holds $1.2 billion in cash and no debt, with analysts raising price targets following the approval.

Stock Market Today

  • Bitcoin Miners Face $19,000 Loss Per BTC Amid Falling Difficulty and Rising Costs
    March 22, 2026, 5:18 AM EDT. Bitcoin miners are losing about $19,000 on every BTC produced, driven by a network difficulty drop of 7.8% and surging energy costs tied to the Middle East conflict. The average cost to mine one bitcoin stands at $88,000, while the market price is near $69,200, pushing miners into an average 21% loss. Mining difficulty has fallen nearly 10% since the year's start, with hashrate retreating from last year's peak. Rising oil prices, disruption at the Strait of Hormuz, and geopolitical risks elevate mining expenses. Miners are coping by diversifying into AI and computing sectors. The next difficulty adjustment in April may decrease further, signaling continued stress and a shrinking miner base, impacting bitcoin's market structure beyond just the mining sector.
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