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NASDAQ:CRNX 26 September 2025 - 7 July 2026

Crinetics Pharmaceuticals (CRNX) Stock Drops After CMO Departure Filing: Latest News, Analyst Forecasts, and What’s Next (Dec. 18, 2025)

Crinetics Pharmaceuticals (CRNX) Stock Drops After CMO Departure Filing: Latest News, Analyst Forecasts, and What’s Next (Dec. 18, 2025)

Crinetics Pharmaceuticals, Inc. stock slid sharply on Thursday, December 18, 2025, after a regulatory filing revealed a leadership transition involving the company’s Chief Medical and Development Officer. In trading, CRNX fell roughly 8% to around the mid‑$40s, with the day’s range stretching from the low‑$40s to the high‑$40s as investors digested the update. Investing.com
18 December 2025
Massive Moves: Record Deals, FDA Wins & Crypto Mania Propel Top Stock Gainers (Sep 29, 2025)

Massive Moves: Record Deals, FDA Wins & Crypto Mania Propel Top Stock Gainers (Sep 29, 2025)

Even as a possible U.S. government shutdown loomed on Capitol Hill, Wall Street managed a modest rise on September 29, 2025. The tech-heavy Nasdaq Composite climbed about 0.5% on the day reuters.com, with investors largely shrugging off fiscal uncertainty. “Investors are clinging to the positives,” noted one strategist, citing hopes of future interest rate cuts and solid economic data reuters.com. Against this cautiously optimistic backdrop, a handful of individual stocks delivered outsized gains thanks to company-specific catalysts – from blockbuster M&A deals to drug approvals and speculative frenzies. Below, we break down the day’s top gainers on U.S. markets and what drove their explosive moves.
Crinetics (CRNX) Stock Skyrockets on FDA Approval – Full 2025 Investor Update

Crinetics (CRNX) Stock Skyrockets on FDA Approval – Full 2025 Investor Update

Crinetics stock has been volatile but trending upward in 2025, with the recent FDA catalyst propelling it sharply higher. On September 26, 2025, CRNX closed around $45–$46, up roughly +28% in a single day reuters.com. This spike followed the Palsonify approval news and likely a short squeeze, given the high short interest prior to the decision marketbeat.com marketbeat.com. The one-year trading range spans $24.10 – $62.53 marketbeat.com, meaning the stock is now nearly double its 52-week low and about 26% below its 2023 high. In other words, even after the recent surge to the mid-$40s, CRNX trades mid-range of its past year’s spectrum.
AI PORTFOLIO

Top Stock Picks

Today’s highest-ranked model selections.

#1 STRONG BUY

NVIDIA

Nvidia (NASDAQ:NVDA) 91/100 ★★★★★
#2 STRONG BUY

Micron Technology

Micron Technology (NASDAQ:MU) 89/100 ★★★★☆
#3 BUY

Alphabet

Alphabet (NASDAQ:GOOGL) 88/100 ★★★★☆
#4 BUY ON PULLBACK

Applied Materials

Applied Materials (NASDAQ:AMAT) 86/100 ★★★★☆
#5 BUY

Taiwan Semiconductor Manufacturing

Shares of NYSE:TSM 85/100 ★★★★☆
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Editorial model selection. Not personalised advice.
MARKET CALENDAR

Key Events Today

The catalysts most likely to move markets.

#01

08:30 ET housing cluster

Surprising starts and permits data can impact homebuilders, mortgage-sensitive stocks, Treasury yields, and the dollar if results deviate significantly from consensus estimates.

#02

Home Depot Q2

The results and outlook provide key insights into housing turnover, renovation demand, professional customer activity, and U.S. discretionary spending.

#03

09:15 ET industrial production

A robust or disappointing factory or utilities report can shift expectations for economic growth, cyclical stocks, bond yields, and the Federal Reserve’s policy direction.

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Times and estimates may change. Verify before trading.