Today: 29 April 2026
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NASDAQ:VRTX 27 June 2025 - 25 April 2026

CRISPR Therapeutics Stock Just Lost 12%: What Casgevy Must Prove Next

CRISPR Therapeutics Stock Just Lost 12%: What Casgevy Must Prove Next

CRISPR Therapeutics shares fell 11.6% Friday, closing at $48.79 with no new company disclosures. The company reported $116 million in 2025 Casgevy revenue and ended the year with $1.98 billion in cash. A June 4 shareholder meeting will vote on expanding the capital band and carrying forward a CHF 1.89 billion net loss. In March, CRISPR raised $536.3 million from a convertible notes offering.
Vertex Pharmaceuticals Stock Falls 4.6% After FDA Label Warning Hits Alyftrek, Trikafta

Vertex Pharmaceuticals Stock Falls 4.6% After FDA Label Warning Hits Alyftrek, Trikafta

Vertex Pharmaceuticals shares fell 4.6% to $433.07 Friday after updated U.S. safety warnings on its cystic fibrosis drugs Alyftrek and Trikafta cited reports of serious neuropsychiatric events. The new labels advise close monitoring for symptoms such as depression and suicidal thoughts. Vertex expects 2026 revenue to remain heavily dependent on cystic fibrosis treatments, despite ongoing efforts to expand its pipeline.
Vertex stock jumps nearly 6% on Oppenheimer upgrade as traders size up new drug pipeline

Vertex stock jumps nearly 6% on Oppenheimer upgrade as traders size up new drug pipeline

Vertex shares jumped 5.7% to $491.47 Friday after Oppenheimer upgraded the stock, citing growth plans beyond cystic fibrosis. The company set 2026 revenue guidance at up to $13.1 billion, with at least $500 million expected from new products. Vertex highlighted gene-editing, pain, and kidney therapies in its outlook. U.S. markets close Monday for Presidents Day.
Vertex stock jumps 4% as earnings date nears — what traders watch next for VRTX

Vertex stock jumps 4% as earnings date nears — what traders watch next for VRTX

Vertex Pharmaceuticals shares rose 4.31% to $461.14, extending gains for a third session with trading volume above the 50-day average. The company will report fourth-quarter and full-year 2025 results after the U.S. market closes on Feb. 12, followed by a conference call. Director Bruce I. Sachs received 107.088 deferred stock units, according to a Jan. 15 regulatory filing.
CRISPR Therapeutics stock slides after CFO share-sale filing; JPM conference next

CRISPR Therapeutics stock slides after CFO share-sale filing; JPM conference next

CRISPR Therapeutics shares fell 4.3% to $54.00 after a filing showed CFO Raju Prasad exercised and sold 29,700 shares under a preset trading plan. The move comes ahead of the company’s Jan. 12 slot at the J.P. Morgan Healthcare Conference and an expected mid-February earnings report. Gene-editing peers also traded lower. CASGEVY revenue and rollout remain key investor focus.
CRISPR Therapeutics stock (CRSP) slips into 2026 as New Year’s Day shuts Wall Street — what investors watch next

CRISPR Therapeutics stock (CRSP) slips into 2026 as New Year’s Day shuts Wall Street — what investors watch next

CRISPR Therapeutics shares closed down 1.4% at $52.44 on Dec. 31, the final trading day of 2025. U.S. markets were shut Jan. 1 for New Year’s. Investors are watching for early-2026 updates on Casgevy’s rollout and the next earnings schedule as trading resumes Jan. 2. Biotech ETFs were little changed in light year-end trading.
Vertex Pharmaceuticals (VRTX) Stock Week Ahead: Holiday-Shortened Trading, New Gene-Therapy Data, and Fresh Analyst Targets (Dec. 22–26, 2025)

Vertex Pharmaceuticals (VRTX) Stock Week Ahead: Holiday-Shortened Trading, New Gene-Therapy Data, and Fresh Analyst Targets (Dec. 22–26, 2025)

Vertex Pharmaceuticals shares closed at $456.20 on Dec. 19, up 2% with higher-than-usual trading volume ahead of a holiday-shortened week. New data for CASGEVY showed children ages 5–11 remained free of crises or transfusions for at least 12 months, but one patient died from busulfan-related complications. Vertex plans global filings in 2026. Morgan Stanley upgraded the stock to Overweight in December.
22 December 2025
Vertex Pharmaceuticals (VRTX) Stock News, Forecasts and Analyst Outlook on Dec. 20, 2025: Casgevy Pediatric Data, Kidney Pipeline Momentum, and Journavx Launch Watch

Vertex Pharmaceuticals (VRTX) Stock News, Forecasts and Analyst Outlook on Dec. 20, 2025: Casgevy Pediatric Data, Kidney Pipeline Momentum, and Journavx Launch Watch

Vertex Pharmaceuticals reported new pediatric results for Casgevy on Dec. 6, showing all four children with severe sickle cell disease were free of vaso-occlusive crises for at least 12 months. Twelve pediatric beta thalassemia patients remained transfusion-free for at least a year. Vertex plans global regulatory filings in 2026. One TDT patient died from busulfan-related complications.
Vertex Pharmaceuticals (VRTX) Stock After Hours on Dec. 19, 2025: Today’s News, Analyst Forecasts, and What to Know Before Monday’s Market Open

Vertex Pharmaceuticals (VRTX) Stock After Hours on Dec. 19, 2025: Today’s News, Analyst Forecasts, and What to Know Before Monday’s Market Open

Vertex Pharmaceuticals closed up 1.97% at $456.20 Friday, ending a three-day slide on volume of about 5.56 million shares, far above its 50-day average. After-hours trading was quiet, with the stock quoted near $456.49 as of 7:40 p.m. ET. No major company news drove the move; trading reflected broad market gains and heavy year-end positioning.
Vertex Pharmaceuticals (VRTX) Stock: What to Know Before the Market Opens on Dec. 15, 2025

Vertex Pharmaceuticals (VRTX) Stock: What to Know Before the Market Opens on Dec. 15, 2025

Vertex Pharmaceuticals shares closed Friday at $452.04, up 1.37%, extending a three-day rally but still 13% below the March high of $519.68. Trading volume topped 1.6 million shares, above the 50-day average. A Morgan Stanley upgrade and optimism over Vertex’s kidney disease pipeline have driven recent swings. New pediatric data for gene-editing therapy Casgevy drew attention at the ASH meeting.
Vertex Pharmaceuticals (VRTX) Stock: This Week’s News, Analyst Forecasts, and the Week-Ahead Outlook (Updated Dec. 12, 2025)

Vertex Pharmaceuticals (VRTX) Stock: This Week’s News, Analyst Forecasts, and the Week-Ahead Outlook (Updated Dec. 12, 2025)

Vertex Pharmaceuticals shares closed at $452.04 Friday, up 2.26% for the week after rebounding from early losses. The move followed new pediatric data for CASGEVY, showing children ages 5–11 with sickle cell disease remained crisis-free for at least 12 months. Vertex plans global regulatory submissions in 2026. One beta thalassemia patient died from pre-transplant chemotherapy complications.
Vertex Pharmaceuticals (VRTX) Stock on December 7, 2025: Casgevy Breakthrough, Pain-Drug Setbacks and What 2026 Forecasts Are Saying

Vertex Pharmaceuticals (VRTX) Stock on December 7, 2025: Casgevy Breakthrough, Pain-Drug Setbacks and What 2026 Forecasts Are Saying

Vertex Pharmaceuticals shares closed at $455.48 on December 5, 2025, valuing the company at about $115–116 billion. New data presented December 6 showed CASGEVY gene therapy achieved 12-month crisis- and transfusion-free outcomes in children 5–11 with sickle cell disease and beta thalassemia, though one pediatric patient died from transplant complications. Vertex plans global regulatory filings for this age group in early 2026.
Martian Life Clues, Hawking Vindication, and More – Science News Roundup (Sept 11–12, 2025)

Martian Life Clues, Hawking Vindication, and More – Science News Roundup (Sept 11–12, 2025)

NASA’s Perseverance rover detected Martian mudstone with minerals resembling those formed by microbes on Earth, raising the possibility of ancient life, though not confirmed. Physicists confirmed Hawking’s black hole area theorem using data from a 2025 black hole merger. A unique gamma-ray burst lasting up to 1,000 times longer than normal puzzled astronomers. Stem-cell therapy let most type 1 diabetes patients stop insulin for over a year.
12 September 2025
Breakthrough Cures, Big Deals, and Global Health Alerts – Biotech & Health News Roundup (Aug 16–17, 2025)

Breakthrough Cures, Big Deals, and Global Health Alerts – Biotech & Health News Roundup (Aug 16–17, 2025)

Pfizer’s sickle cell drug inclacumab failed a Phase 3 trial, missing its main goal and deepening setbacks from its $5.4 billion Global Blood Therapeutics acquisition. In contrast, Pfizer and Merck’s Padcev-Keytruda combo improved survival in muscle-invasive bladder cancer. Novo Nordisk’s Wegovy won FDA approval for treating metabolic dysfunction-associated steatohepatitis.
June 2025 Science Breakthroughs and Projects: Medicine, Space, Climate, AI & More

June 2025 Science Breakthroughs and Projects: Medicine, Space, Climate, AI & More

Cancer cells siphon mitochondria from nerve cells through microscopic tubes, aiding metastasis, a Nature study found. Tumor DNA was detected in blood years before diagnosis, offering early screening potential. Casgevy, a CRISPR-based sickle-cell therapy, has treated over 90 patients since late 2024. NASA’s James Webb Space Telescope directly imaged exoplanet TWA-7b, a Saturn-mass gas giant.
Top Biotechnology and Health Tech Trends in 2025: Mid-Year Update and Forecast (Updated: June 27th, 2025)

Top Biotechnology and Health Tech Trends in 2025: Mid-Year Update and Forecast (Updated: June 27th, 2025)

The FDA approved Abeona’s Zevaskyn, the first cell-based gene therapy for RDEB, in April 2025, with launch set for Q3 at $3.1 million. Vertex’s CRISPR therapy Casgevy generated $2 million in Q3 2024. Novo Holdings acquired Catalent for $16.5 billion in January 2025 to secure GLP-1 drug manufacturing. Johnson & Johnson bought Intra-Cellular Therapies for $14.6 billion, expanding its neuroscience portfolio.

Stock Market Today

  • ASX Midday Update: Utilities Rise Amid Middle East Tensions, Materials Decline
    April 28, 2026, 11:27 PM EDT. Utilities stocks led the Australian Securities Exchange mid-session rally, rising 1.7% after the United Arab Emirates announced its exit from OPEC, fueling energy supply worries amid US-Iran tensions. Origin Energy shares climbed nearly 3%, rebounding from previous losses. Conversely, the materials sector fell 0.8%. Westgold Resources dropped over 2% following its quarterly gold production report of 93,145 ounces and an increased all-in sustaining cost to AU$3,338 per ounce from AU$2,829 last year. The contrasting movements underscore sector sensitivity to geopolitical and operational factors affecting Australia's markets today.

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AST SpaceMobile Stock’s May 11 Moment: FCC Win Meets BlueBird 7 Reality

AST SpaceMobile Stock’s May 11 Moment: FCC Win Meets BlueBird 7 Reality

29 April 2026
AST SpaceMobile will hold its first-quarter update call on May 11 after winning FCC approval to deploy a 248-satellite constellation for direct-to-device service. Shares fell 6.8% Tuesday, following the loss of its BlueBird 7 satellite in a failed launch. The company expects insurance to cover the loss and is targeting 45 satellites in orbit by end-2026. Investors are watching launch progress and commercial service timing.
OpenAI Target Miss Report Sends Oracle, CoreWeave and AI Stocks Lower

OpenAI Target Miss Report Sends Oracle, CoreWeave and AI Stocks Lower

29 April 2026
Oracle shares fell 4% and CoreWeave dropped 5.9% Tuesday after a Wall Street Journal report said OpenAI missed recent revenue and user targets. Nvidia, AMD, and Arm Holdings also declined, with the iShares Semiconductor ETF down 3.7%. OpenAI denied internal divisions and said its AI coding product Codex reached 4 million users. Oracle’s credit default swaps hit a two-week high amid concern over its $300 billion cloud deal with OpenAI.
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