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NASDAQ:IOVA 3 November 2025 - 23 December 2025

Iovance Biotherapeutics (IOVA) Stock News Today: Barclays Raises Target, Short-Interest Pressure, and 2026 Catalysts (Dec. 23, 2025)

Iovance Biotherapeutics (IOVA) Stock News Today: Barclays Raises Target, Short-Interest Pressure, and 2026 Catalysts (Dec. 23, 2025)

Iovance Biotherapeutics shares jumped 12.1% to close at $2.78 on Dec. 22, with pre-market trading near $2.80. Short interest stands at 33.4% of the float, or about 118.94 million shares, according to MarketBeat. Barclays raised its price target to $10 and kept an Overweight rating. Iovance also announced inducement stock options for four new employees at a $2.46 exercise price.
23 December 2025
Iovance Biotherapeutics (IOVA) Q3 2025: Revenue Climbs ~13% to ~$68M; Gross Margin Hits 43%, Guidance Reaffirmed — November 6, 2025

Iovance Biotherapeutics (IOVA) Q3 2025: Revenue Climbs ~13% to ~$68M; Gross Margin Hits 43%, Guidance Reaffirmed — November 6, 2025

Iovance Biotherapeutics reported Q3 2025 revenue of $67.5 million, up 13% sequentially but below analyst expectations, and a net loss of $91.3 million, or $0.25 per share. Gross margin rose to 43%. Management reaffirmed full-year revenue guidance of $250–$300 million. Over 80 U.S. treatment centers are now active, and cash reserves totaled $307 million at quarter’s end.
6 November 2025
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Iovance Biotherapeutics (IOVA): TIL Cancer Breakthrough or Biotech Bust?

Iovance Biotherapeutics (IOVA): TIL Cancer Breakthrough or Biotech Bust?

Iovance shares traded near $2.00 on Nov. 3, 2025, with a market cap around $700 million after plunging 70% year-to-date. The company’s Amtagvi, the first FDA-approved TIL therapy for advanced melanoma, also secured Health Canada approval. Interim Phase 2 data showed a 25.6% response rate for lifileucel in advanced NSCLC. Iovance will hold its Q3 earnings call on Nov. 6.
3 November 2025

Stock Market Today

  • Dow Rises 276 Points; Nasdaq and S&P 500 Also Gain
    May 21, 2026, 6:16 PM EDT. U.S. stocks moved higher on Thursday with the Dow Jones Industrial Average climbing 276 points. The Nasdaq Composite rose 23 points, while the S&P 500 increased by 13 points. The gains followed a reversal in oil prices, impacting market sentiment. Investors reacted positively to the latest developments in energy markets, contributing to a broadly upward trend across major indexes.

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