Polyrizon (PLRZ) Stock Doubles on Naloxone Hydrogel Breakthrough and PL‑14 Manufacturing Milestone – What Investors Need to Know on December 4, 2025
Polyrizon Ltd. shares surged to $13–15 by early afternoon December 4, more than doubling from the previous close of $7.09, after hitting intraday highs above $18. The rally followed news of a manufacturing milestone for its PL‑14 allergy nasal spray and new preclinical data showing improved mucoadhesion for its naloxone hydrogel. Polyrizon, based in Israel, has no approved products and reported a 2024 net loss of about $1.5 million.