Corcept Therapeutics (CORT) stock dives nearly 50% after FDA rejects relacorilant — what investors watch next

Shares of Corcept Therapeutics Incorporated sank nearly 50% on Wednesday after the U.S. Food and Drug Administration issued a complete response letter for the company’s relacorilant application in hypertension secondary to hypercortisolism, also known as Cushing’s syndrome. The stock was down 49.7% at $35.31 in afternoon trading. Nasdaq

Vanda (VNDA) stock jumps 28% after FDA approves Nereus motion-sickness drug

Vanda (VNDA) stock jumps 28% after FDA approves Nereus motion-sickness drug

Vanda Pharmaceuticals shares jumped 28.1% to $9.01 at 1:38 p.m. ET on Wednesday after the company said the U.S. Food and Drug Administration approved Nereus to prevent vomiting induced by motion. Vanda said the oral drug is a neurokinin-1 receptor antagonist — meaning it blocks a receptor involved in nausea signaling — and called it the first new pharmacologic motion-sickness treatment in more than four decades. In late-stage Phase 3 trials — the final stage before approval — vomiting rates were about 10%–20% on Nereus versus 38%–44% on placebo, and Vanda said it expects to launch the drug in coming months. PR Newswire
31 December 2025
Johnson & Johnson stock today: JNJ slips after $3.05B Halda cancer deal closes, Barclays lifts target

Johnson & Johnson stock today: JNJ slips after $3.05B Halda cancer deal closes, Barclays lifts target

Johnson & Johnson shares edged lower on Tuesday after the company said it completed its $3.05 billion cash purchase of cancer-therapy developer Halda Therapeutics. The stock was down about 0.2% at $207.12 in midday trading. Executive vice president Jennifer Taubert called the closing a “strategic milestone” as J&J flagged about $0.20 of dilution to adjusted earnings per share — profit per share excluding certain one-time items — split between 2025 and 2026. Johnson & Johnson Investor Relations
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