Marcin Frąckiewicz

What to Know Before Markets Open on October 20, 2025 FDA Breakthrough News Ignites Rally Spruce Biosciences’ meteoric rise began with a game-changing regulatory win. On October 6, the company announced that the FDA had granted Breakthrough Therapy Designation (BTD) to its lead drug, tralesinidase alfa (TA-ERT)ts2.tech. TA-ERT is an experimental enzyme replacement therapy targeting Sanfilippo Syndrome Type B (also known as MPS IIIB) – a rare, inherited lysosomal storage disease that causes severe neurological decline in childrenstocktwits.com. The FDA’s BTD endorsement signals that early data for TA-ERT show “substantial improvement” over existing options for this deadly disease, and it

Record Festive Spending Despite Sky-High Gold Prices Dhanteras 2025 – the traditional gold-buying festival – has shattered spending records in India. Consumers spent an estimated ₹1 trillion (₹1 lakh crore) over the Dhanteras period, driven largely by precious metals demandindiatoday.in. According to the Confederation of All India Traders (CAIT), gold and silver purchases alone accounted for about ₹60,000 crore, marking a 25% jump in value from last year’s festivalindiatoday.in. This is remarkable given how much gold prices have climbed: gold was around ₹1,30,000–₹1,34,000 per 10 grams in the run-up to Dhanteras – roughly 60–63% higher than last Dhanterasindiatoday.inlivemint.com. In fact,