Eli Lilly (LLY) Stock: What to Know Before the U.S. Market Opens on Dec. 22, 2025
Eli Lilly shares closed at $1,071.44 on Dec. 19, near record highs, as new late-stage data for oral GLP-1 candidate orforglipron showed less weight regain versus placebo after switching from injectables. Retatrutide posted 28.7% average weight loss in a Phase 3 trial. Lilly cut Zepbound prices in the U.S. and Canada. Orforglipron could receive FDA approval as early as March 2026.