June 2025 Science Breakthroughs and Projects: Medicine, Space, Climate, AI & More
In a Nature study, cancer cells were shown to siphon mitochondria from nearby nerve cells via microscopic tubes, a mechanism called mitochondrial hijacking that promotes metastasis. A separate Science News report described tumor DNA detectable in blood years before diagnosis, boosting early cancer screening prospects. An in vivo “exercise in a pill” approach in mice used a molecule that mimics workout benefits, improving metabolic health. Casgevy, the CRISPR-based sickle-cell gene therapy approved in late 2024, has begun treatment in over 90 patients globally. CRISPR Therapeutics’ CTX310, an in vivo ANGPTL3-targeting CRISPR therapy, produced dose-dependent triglyceride reductions up to 82% and
